Email this article ASSESSMENT OF SYSTEMIC INFLAMMATORY RESPONSE INDICATORS AS PREDICTORS FOR CHRONIC RENAL ALLOGRAFT DYSFUNCTION
- Authors: Solomatina L.V.1,2,3, Zhuravleva I.A.1,2, Groznykh E.V.4
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Affiliations:
- Institute of Immunology and Physiology of the UB RAS
- Ural Federal University named after the first President of Russia B. N. Yeltsin
- Urals Scientific Research Institute for Maternal and Child Care
- Sverdlovsk Regional Hospital № 1
- Issue: Vol 20, No 3 (2017)
- Pages: 508-510
- Section: Articles
- URL: https://rusimmun.ru/jour/article/view/746
- ID: 746
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Abstract
The article present the results of a study of the diagnostic efficacy of various SIR indicators (IL-6, IL-8, IL-10, TNFa, CRP), duration of dialysis before renal transplantation, post-allotransplantation period and HLA mismatch score (the number of mismatches from 6 antigens HLA loci A, B, DR) with respect to the development of chronic renal allograft dysfunction (CRAD). It was shown that the level of proinflamma-tory cytokine TNFa is a promising marker for the prognosis of the CRAD development.
About the authors
L. V. Solomatina
Institute of Immunology and Physiology of the UB RAS; Ural Federal University named after the first President of Russia B. N. Yeltsin; Urals Scientific Research Institute for Maternal and Child Care
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
Iu. A. Zhuravleva
Institute of Immunology and Physiology of the UB RAS; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: noemail@neicon.ru
Russian Federation
E. V. Groznykh
Sverdlovsk Regional Hospital № 1
Email: noemail@neicon.ru
Russian Federation
References
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- Гусев Е. Ю., Соломатина Л. В., Паньшина Е. В., Журавлева Ю. А., Зубова Т. Э. Системное воспаление при хронической дисфункции трансплантированной почки. Нефрология и диализ. 2011, 2, 82-88.
- Гусев Е. Ю., Соломатина Л. В., Журавлева Ю. А., Зубова Т. Э. Системная воспалительная реакция у больных с терминальной хронической почечной недостаточностью. Нефрология и диализ. 2008, 3-4, 248-253.
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