Russian Journal of ImmunologyRussian Journal of Immunology1028-72212782-7291Russian Society of Immunology20010.31857/S102872210006947-6Research ArticleASSESSMENT OF CORRELATION BETWEEN CYTOKINE STATUS AND RED CELL DISTRIBUTION WIDTH IN PATIENTS WITH ATHEROSCLEROSIS OF LOWER LIMBS AFFECTED BY DIABETES MELLITUS TYPE 2SavchukK. S.<p>chief operating officer,</p><p>Chelyabinsk</p>ksenyasavchuk@gmail.comRyabovaL. V.<p>holder of Habilitation degree in medicine, professor of Propaedeutics of Internal Diseases,</p><p>Chelyabinsk</p>fake@neicon.ruNikushkinaK. V.<p>senior researcher of Research institute of immunology,</p><p>Chelyabinsk</p>fake@neicon.ruNikonovaT. I.<p>senior assistant of Research institute of immunology,</p><p>Chelyabinsk</p>fake@neicon.ruMunicipal budgetary healthcare institution city clinic outpatient clinic No 8Federal state budgetary educational institution of higher education “South Ural State Medical University”15042019222-15095111405202014052020Copyright © 2019, Savchuk K.S., Ryabova L.V., Nikushkina K.V., Nikonova T.I.2019<p>Researchs objective is to make an analysis of correlations between index of systemic inflammation and red cell distribution width in patients with diabetes mellitus type 2 aff ected by atherosclerosis of lower limbs. 40 patients with diabetes mellitus were examined. Using Spearmen rank correlation, statistically signifi cant correlations between IL-1 and red cell distribution width were discovered (r=0,358; p=0,027). Herewith there is no signifi cant correlation between IL-6, IL-8, IL-10, TNF- and red cell distribution width.</p>diabetes mellitus type 2atherosclerotic disease of lower limb’s arteryred cell distribution widthcytokine statusIL-1βсахарный диабет 2 типаатеросклероз артерий нижних конечностейкоэффициент анизотропии эритроцитовцитокиновый статусИЛ-1β[1. Тарасов А. А., Резникова Е. А., Давыдов С. И., Бочкарева О. И., Бабаева А. Р. Клиническое и прогностическое значение маркеров эндотелиальной дисфункции при атеросклероз-ассоциированных сосудистых поражениях Медицинский алфавит, 2016, № 30(293), Т. 3., С. 5–11.][2. Malandrino N., Wu W., Taveira T. Association between red blood cell distribution width and macrovascular and microvascular complications in diabetes. Diabetologia, 2012, 55 (1), 226–235.][3. de Gonzalo-Calvo D., de Luxan-Delgado B., RodrgiuezGonzalez S. Interleukin 6, soluble tumor necrosis factor receptor I and red blood cell distribution width as biological markers of functional dependence in an elderly population: a translational approach. Cytokine, 2012, 58 (2), 193–198.]