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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Immunology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Immunology</journal-title><trans-title-group xml:lang="ru"><trans-title>Russian Journal of Immunology</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1028-7221</issn><issn publication-format="electronic">2782-7291</issn><publisher><publisher-name xml:lang="en">Russian Society of Immunology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">750</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">FACTORS OF INNATE IMMUNITY IN WOMEN WITH ABDOMINAL OBESITY AND OVERWEIGHT, THEIR RELATIONSHIP WITH PARAMETRES OF CARBOHYDRATE AND LIPID METABOLISM</article-title><trans-title-group xml:lang="ru"><trans-title>ФАКТОРЫ ВРОЖДЁННОГО ИММУНИТЕТА У ЖЕНЩИН С АБДОМИНАЛЬНЫМ ОЖИРЕНИЕМ И ИЗБЫТКОМ МАССЫ ТЕЛА, ИХ ВЗАИМОСВЯЗЬ С СОСТОЯНИЕМ УГЛЕВОДНОГО И ЛИПИДНОГО ОБМЕНА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sumerkina</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Сумеркина</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Golovneva</surname><given-names>E. S.</given-names></name><name xml:lang="ru"><surname>Головнева</surname><given-names>Е. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">South Ural State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО ЮУГМУ Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2017</year></pub-date><volume>20</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>517</fpage><lpage>519</lpage><history><date date-type="received" iso-8601-date="2020-10-22"><day>22</day><month>10</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Sumerkina V.A., Golovneva E.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Сумеркина В.А., Головнева Е.С.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Sumerkina V.A., Golovneva E.S.</copyright-holder><copyright-holder xml:lang="ru">Сумеркина В.А., Головнева Е.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://rusimmun.ru/jour/article/view/750">https://rusimmun.ru/jour/article/view/750</self-uri><abstract xml:lang="en"><p>The study evaluated the state of innate immunity in young women with abdominal obesity and overweight. In women with isolated abdominal obesity the activation of neutrophil function was observed. During the progression of obesity in young women the decreasing of parameters of phagocytosis was revealed. It was associated with increased volume of abdominal fat tissue and disorders of lipid and carbohydrate metabolism.</p></abstract><trans-abstract xml:lang="ru"><p>В исследовании оценивали состояние некоторых показателей врождённого иммунитета у молодых женщин с абдоминальным ожирением и избытком массы тела. При накоплении жировой ткани первоначально (при изолированном абдоминальном ожирении) происходит активация функции нейтрофилов, что, вероятно, носит компенсаторный характер. По мере формирования и прогрессирования ожирения у молодых женщин наблюдается снижение функционального резерва фагоцитов, что ассоциировано с увеличением объема жировой ткани и изменениями липидного и углеводного обмена.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>абдоминальное ожирение</kwd><kwd>избыток массы тела</kwd><kwd>врожденный иммунитет</kwd><kwd>дислипидемия</kwd><kwd>abdominal obesity</kwd><kwd>overweight</kwd><kwd>innate immunity</kwd><kwd>dyslipidemia</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Шляхто Е. В., Недогода С. В., Конради А. О., Баранова Е. И., Фомин В. В. и др. Концепция новых национальных клинических рекомендаций по ожирению. Рос.кардиол. журн. 2016, 4, 7-13.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Плохая А. А. Современные аспекты лечения ме-таболическогосиндрома. 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