Russian Journal of ImmunologyRussian Journal of Immunology1028-72212782-7291Russian Society of Immunology759CONDITION OF CELLULAR AND HUMORAL LINKS OF IMMUNITY IN CHILDREN WITH COMMUNITY-ACQUIRED PNEUMONIA IN CHELYABINSK CITYUzunovaA. N.noemail@neicon.ruNikushkinaK. V.noemail@neicon.ruIzyurovaN. V.noemail@neicon.ruPushkarevaO. S.noemail@neicon.ruFSBEI of HI “South-Ural State Medical University" of the Ministry of Healthcare of the Russian FederationResearch institute of immunology1507201720353854022102020Copyright © 2017, Uzunova A.N., Nikushkina K.V., Izyurova N.V., Pushkareva O.S.2017In pediatric patients, pneumonia is one of the most urgent problems of modern medicine and the most important single cause of death in children worldwide. One of the leading causes of pneumonia at the present time is the change in the immunological reactivity of the organism. To identify features of the immune status, namely cellular and humoral links of immunity in children, we examined a total of 86 children aged 1 year to 18 years. All the children were divided into 2 groups: the first group of 60 children with a diagnosis of community-acquired pneumonia, the second group consisted of 26 healthy children of corresponding age and sex. Thus revealed the imbalance of cellular and humoral immunity in children with community-acquired pneumonia. Studies of the immune status in patients with pneumonia indicate a decrease in levels of serum immunoglobulins and phagocytosis, increased levels of circulating immune complexes.пневмониядетииммунитетиммунограммаPneumoniachildrenimmunityimmunogramm[Ковтун Т. А., Тутельян А. В., Шабалина С. В. Современные представления об эпидемиологии и этиологии острых респираторных заболеваний у детей. Эпидемиология и вакцинопрофи-лактика № 5 (54), 2010, 41-44.][Новиков Ю. К. Пневмонии: сложные и нерешенные вопросы диагностики и лечения. Русский медицинский журнал. 2004. № 21, 1226-1232.][Мейл Д. Иммунология/ Пер. с англ. М.: Логосфе-ра, 2007, 586.][Peakman M, Vergani D. Basic And Clinical Immunology. NY: “Churchill Livingstone”, 1997, 338.]