Russian Journal of ImmunologyRussian Journal of Immunology1028-72212782-7291Russian Society of Immunology88010.31857/S102872210002396-0The reaction of neutrophils in chronic exercise of varying intensityErmolaevaE. .noemail@neicon.ruKantyukovS. .noemail@neicon.ruYakovlevaV. .noemail@neicon.ruSouth Ural State Medical UniversityUral State University of Physical Culture1507201821328628922102020Copyright © 2018, Ermolaeva E..., Kantyukov S..., Yakovleva V...2018<p>In the experiment on rats shows that chronic submaximal exercise and moderate power leads to an increase in neutrophils with change of their functional activity. Chronic physical load of moderate power there is a decrease in chemotaxis. Phagocytic function changes is ambiguous – phagocytosis activity increases and intensity decreases. Chronic submaximal exercise indices of functional activity of leukocytes remain within the control values.</p>physical activitychemotaxisphagocytosisфизическая нагрузкахемотаксисфагоцитоз[Walsh N. P., Gleeson M., Shephard R. J., Woods J. A. et al. Position statement. Part 1: Immune function and exercise. Exerc Immunol Rev, 2011, 17, 6–63.][Ермолаева Е. Н., Кривохижина Л. В., Кантюков С. А. и др. Изменение лейкоцитарных индексов при хронической физической нагрузке. Российский иммунологический журнал, 2013, 7(16),2–3(1), 36–38.][Волчегорский И. А., Долгушин И. И., Колесников О. Л., Цейликман В. Э. Экспериментальное моделирование и лабораторная оценка адаптивных реакций организма. Челябинск: Изд-во ЧГПУ, 2000, 167.][Smith C., Kruger M. J., Smith R. M., Myburgh K. H. The infl ammatory response to skeletal muscle injury: illuminating complexities. Sports Med, 2008, 38(11), 947–969.][Tidball J. G. Mechanisms of muscle injury, repair, and regeneration. Compr Physiol, 2011, 1(4), 2029–2062.][Peake J. M. Exercise-induced alterations in neutrophil degranulation and respiratory burst activity: possible mechanisms of action. Exerc Immunol Rev, 2002, 8, 49–100.][Melnikov I. Y., Zhurilo О. V., Komarova I. A, Sashenkov S. L. Humoral factors of immunity depending on the skill levels of athletes. Gazzetta Medica Italiana – Archivio per le Scienze Mediche, 2018, 177 (Suppl. 1, N3), 56–61.][Malm C. Susceptibility to infections in elite athletes: the S-curve. Scand J Med Sci Spor, 2006, 16(1), 4–6][Handzlik M. K., Shaw A. J., Dungey M., Bishop N. C., Gleeson M. The infl uence of exercise training status on][antigen-stimulated IL-10 production in whole blood culture and numbers of circulating regulatory T cells. Eur J Appl Physiol, 2013, 113(7), 1839–1848.]