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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Immunology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Immunology</journal-title><trans-title-group xml:lang="ru"><trans-title>Russian Journal of Immunology</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1028-7221</issn><issn publication-format="electronic">2782-7291</issn><publisher><publisher-name xml:lang="en">Russian Society of Immunology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">906</article-id><article-id pub-id-type="doi">10.31857/S102872210002422-9</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Diverse and cross-linking sensitization in asthma and other atopic allergic conditions</article-title><trans-title-group xml:lang="ru"><trans-title>Многообразная и перекрестная сенсибилизация у больных астмой и другими атопическими аллергическими заболеваниями</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sviridova</surname><given-names>V. .</given-names></name><name xml:lang="ru"><surname>Свиридова</surname><given-names>В. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Isaev</surname><given-names>P. .</given-names></name><name xml:lang="ru"><surname>Исаев</surname><given-names>П. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Romanova</surname><given-names>M. .</given-names></name><name xml:lang="ru"><surname>Романова</surname><given-names>М. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Koshkarova</surname><given-names>N. .</given-names></name><name xml:lang="ru"><surname>Кошкарова</surname><given-names>Н. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Koshovkina</surname><given-names>T. .</given-names></name><name xml:lang="ru"><surname>Кошовкина</surname><given-names>Т. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shkatova</surname><given-names>A. .</given-names></name><name xml:lang="ru"><surname>Шкатова</surname><given-names>А. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Siberian State Medical University</institution></aff><aff><institution xml:lang="ru">Сибирский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Student Polyclinic Hospital</institution></aff><aff><institution xml:lang="ru">ОГАУЗ Межвузовская поликлиника</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2018</year></pub-date><volume>21</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>428</fpage><lpage>433</lpage><history><date date-type="received" iso-8601-date="2020-10-22"><day>22</day><month>10</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Sviridova V..., Isaev P..., Romanova M..., Koshkarova N..., Koshovkina T..., Shkatova A...</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, Свиридова В.С., Исаев П.Ю., Романова М.И., Кошкарова Н.С., Кошовкина Т.В., Шкатова А.Н.</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Sviridova V..., Isaev P..., Romanova M..., Koshkarova N..., Koshovkina T..., Shkatova A...</copyright-holder><copyright-holder xml:lang="ru">Свиридова В.С., Исаев П.Ю., Романова М.И., Кошкарова Н.С., Кошовкина Т.В., Шкатова А.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://rusimmun.ru/jour/article/view/906">https://rusimmun.ru/jour/article/view/906</self-uri><abstract xml:lang="en"><p>Role of allergen-associated molecular patterns as possible factors in the development of cross-linking sensitization to allergens is described, and diff erent allergens, which may count for much before the choice of allergen-specifi c immunotherapy are elucidated in patients with asthma and other atopic allergic conditions.</p></abstract><trans-abstract xml:lang="ru"><p>В статье освещена возможная роль аллерген-ассоциированных молекулярных паттернов в формировании перекрестной сенсибилизации, а также роль других факторов в патогенезе и выборе тактики лечения больных с астмой и другими атопическими аллергическими заболеваниями методом аллерген-специфической иммунотерапии.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>allergen-associated molecular patterns</kwd><kwd>allergen-specifi c immunotherapy</kwd><kwd>bronchial asthma</kwd><kwd>mold allergens</kwd><kwd>аллерген-ассоциированные молекулярные паттерны</kwd><kwd>аллергенспецифическая иммунотерапия</kwd><kwd>бронхиальная астма</kwd><kwd>грибковые аллергены</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Medzhitov R. 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