STUDY OF NEUTROPHIL COUNT DYNAMICS IN EXPOSED PERSONS DURING THE PERIOD PRIOR TO ACUTE LEUKEMIAS DEVELOPMENT



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Abstract

A retrospective analysis of neutrophil count dynamics in the blood of the exposed residents of the Techa riverside settlements, who subsequently developed acute leukemias, was carried out. The peculiarities in the reaction of granulocyte lineage to radiation in these individuals were found outin comparison with exposed individuals without leukemias.

About the authors

A. A. Akleyev

Urals Research Center for Radiation Medicine of the FMBA of Russia;
Southern-Urals State Medical University of the RF Ministry of Public Health

Author for correspondence.
Email: andrey.akleev@yandex.ru

M.D., PhD, Associate Professor of the Department of Microbiology, Virology, Immunology and Clinical Laboratory Diagnostics,

Chelyabinsk 

Russian Federation

I. I. Dolgushin

Southern-Urals State Medical University of the RF Ministry of Public Health

Email: fake@neicon.ru

M.D., Professor, Academician of the Russian Academy of Sciences, Head of Microbiology, Virology, Immunology and Clinical Laboratory Diagnostics Department,

Chelyabinsk 

Russian Federation

E. A. Blinova

Urals Research Center for Radiation Medicine of the FMBA of Russia;
Chelyabinsk State University

Email: fake@neicon.ru

PhD, Head of Molecular-cell Radiobiology Laboratory;

Associate Professor of the Department of Radiation Biology,

Chelyabinsk

Russian Federation

References

  1. Nikkila A., Erme S., Arvela H., Holmgren O., Raitanen J., Lohi O., Auvinen A. Background radiation and childhood leukemia: A nationwide register-based case-control study. International Journal of Cancer. 2016, 139 (9), 1975–1982.
  2. Аклеев А. В., Варфоломеева Т. А. Состояние гемопоэза в условиях многолетнего облучения костного мозга у жителей прибрежных сёл р. Теча. Радиационная биология. Радиоэкология. 2007, Т. 47 (3), 307–321.

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Copyright (c) 2019 Akleyev A.A., Dolgushin I.I., Blinova E.A.

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