TYPES OF IMMUNE RESPONSE DURING BEDSORES


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Abstract

The aim of the study was the selection on the basis of clinical and immunological studies of the types of immune system response in patients with bedsores.67 patients with acute surgical diseases complicated by bedsores were examined.The study of the phenotype of blood lymphocytes was performed by flow cytometry.For typing of patients with bedsores the cluster analysis method was used.An immunological examination of patients with bedsores found that immunological indicators are characterized by a significant variety.The use of cluster analysis allowed us to isolate immunotype 4 in patients with bedsoreswhich are defined as different pathogenetic variants of the course of the disease.

About the authors

S. A. Borisov

Scientific Research Institute of medical problems of the North

Author for correspondence.
Email: 2410454@mail.ru

Post-Graduate Student, Laboratory of Cell Molecular Physiology and Pathology,

Krasnoyarsk

Russian Federation

A. A. Savchenko

Scientific Research Institute of medical problems of the North

Email: fake@neicon.ru

MD, Professor, Head of the Laboratory of Cell Molecular Physiology and Pathology,

Krasnoyarsk

Russian Federation

E. V. Kasparov

Scientific Research Institute of medical problems of the North

Email: fake@neicon.ru

MD, Professor, Director,

Krasnoyarsk

Russian Federation

M. V. Matsenko

Scientific Research Institute of medical problems of the North

Email: fake@neicon.ru

Post-Graduate Student, Laboratory of Cell Molecular Physiology and Pathology, 

Krasnoyarsk

Russian Federation

I. V. Kudryavtsev

Federal State Budgetary Scientific Institution «Institute of Experimental Medicine»

Email: fake@neicon.ru

Ph.D., Laboratory of General Immunology, 

St. Petersburg

Russian Federation

References

  1. Борисов А. Г. Клиническая характеристика нарушения функции иммунной системы. Медицинская иммунология, 2013, 15(1), 45–50.
  2. Борисов А. Г., Савченко А. А., Соколовская В. К. Заболеваемость, связанная с нарушениями функции иммунной системы (на примере Красноярского края). Здравоохранение Российской Федерации, 2014, 58(6), 38–41.
  3. Борисов А. Г. Кластерный анализ типов иммунных нарушений при инфекционно-воспалительных заболеваниях. Российский иммунологический журнал, 2014, 8(4), 1002–1011.
  4. Борисов А. Г., Савченко А. А., Черданцев Д. В., Здзитовецкий Д. Э., Первова О. В., Кудрявцев И. В., Беленюк В. Д., Шапкина В. А. Типы иммунного реагирования при распространенном гнойном перитоните. Хирургия. Журнал им. Н. И. Пирогова, 2016, 9, 28–34.

Copyright (c) 2019 Borisov S.A., Savchenko A.A., Kasparov E.V., Matsenko M.V., Kudryavtsev I.V.

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