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Studies of CD45+ and CD46+ expression on the peripheral blood lymphocyte subsets of the post-COVID patients
Dobrynina M.A., Zurochka A.V., Komelkova M.V., Luo S., Zurochka V.A., Desheng H., Ryabova L.V., Sarapultsev A.P.
Content of PD-1+ and PD-L1+ peripheral blood lymphocytes in individuals with pollen sensitization before and after allergen-specific immunotherapy
Barkovskaya M.S., Sevastyanov P.V., Demina D.V., Kozlov V.A.
Evaluation of anti-TNF treatment efficiency in children with immune-dependent diseases by means of testing the NF-κB activity in lymphocyte populations
Petrichuk S.V., Radygina T.V., Kuptsova D.G., Kurbatova O.V., Semikina E.L., Murashkin N.N., Potapov A.S., Fisenko A.P.
Dynamics of immune system parameters in development of SARS-CoV-2-specific immunity in a patient with common variable immune deficiency
Sizyakina L.P., Andreeva I.I., Kharitonova M.V.
Factors of inflammatory, adhesiveness and thrombosis in acute lower limb ischemia and dexamethasone therapy
Magamedov I.D., Pivovarova L.P., Nokhrin S.P., Soroka V.V., Ariskina O.B., Osipova I.V., Radjabov I.M., Fomin K.N., Potskhor-ogly S.L., Kolichenko L.V., Markelova E.V., Goncharova O.V.
Features of immune status in children with Wilson–Konovalov disease at different stages of liver fibrosis
Kurbatova O.V., Kuptsova D.G., Bezrukavnikova L.M., Radygina T.V., Movsisyan G.B., Anushenko A.O., Komarova A.D., Potapov A.S., Petrichuk S.V., Fisenko A.P.
Evaluation of specific T cell immune response to SARS-CoV-2 in COVID-19 infection and following Gam-COVID-Vac vaccine prophylaxis
Plekhova N.G., Sitdikova T.S., Dubiy A.A., Mikhailov A.O., Prosekovа E.V.
Immunity parameters in adults with measles compared with healthy persons
Toptygina A.P., Andreev Y.Y.
Assessment of lymphocyte populations and their subsets in the patients with acute coronary syndrome
Safronova E.A., Ryabova L.V.
Flow cytometry assessment of mitochondrial indices in CD4+T cells from peripheral blood
Korolevskaya L.B., Saidakova E.V., Shmagel K.V.
Complex inflammation indexes in patients with post-COVID syndromeНа сегодняшний день в мире активно занимаются выделением новых маркеров, характеризующих тяжесть состояния после перенесенного COVID-19. Для более детального понимания того, какие изменения вызывает вирус SARS-CoV-2 в организме человека и с чем взаимосвязано длительное сохранение симптомов после перенесенной новой коронавирусной инфекции, необходимо оценить связь между степенью тяжести после заболевания и показателями клинического анализа крови. Цель работы – выделение прогностических маркеров по клиническому анализу крови, коррелирующих с тяжестью состояния пациентов после перенесенной новой коронавирусной инфекции. В исследование включены 372 пациента в постковидный период. Исходное течение заболевания оценивалось с использованием шкалы клинического прогрессирования ВОЗ. Разделение пациентов на группы осуществлялось по шкале функционального состояния после COVID-19 (PCFS). В анализе крови обследуемых были выделены критические значения лабораторных показателей, которые были проанализированы на предмет наличия взаимосвязей с тяжестью синдрома. Проведен качественный анализ типов реакции иммунной системы в программе «Протист». Установлены наиболее статистически выраженные изменения у пациентов группы 1. Коэффициенты NLR, LMR, SII при сравнении с группой пациентов 1, 2, 3 были ниже. Индекс PLR был ниже при сравнении с группой пациентов 0. Других статистических различий между группами не выявлено. Поэтому интерес вызывает исследования качественных показателей. В группах больных 0, 1, 2 в основном определяется ареактивность иммунитета (71-92%), а в группах пациентов 3 и 4 уже у половины обследуемых наблюдается активация врожденного иммунитета, активация адаптивного иммунитета и иммунодефицит (угнетение иммунитета). Пациенты группы 2 занимали промежуточное состояние. В постковидный период общие гематологические нарушения не являются выраженными и достаточными для постановки диагноза. В большей степени необходимо ориентироваться на комплексные качественные показатели. Как один из основных качественных параметров у пациентов в постковидный период имеет смысл использовать «Методику определения типа реакции иммунитета по развернутому анализу крови» При этом оценка типа иммунной реакции позволяет не только выявить пациентов с постковидным синдромом, но и провести отбор пациентов, нуждающихся в противовоспалительной и детоксикационной терапии.
Sadovskiy I.S., Kruglova O.S., Savchenko A.A., Sobko E.A., Kasparov E.V., Demko I.V., Borisov A.G.
EFFECT OF PREGNANCY-SPECIFIC β1-GLYCOPROTEIN ON CHEMOKINE PROFILE OF CULTURED T-HELPER AND MONONUCLEAR CELLS
Zamorina S.A., Litvinova L.S., Yurova K.A., Khaziakhmatova O.G., Timganova V.P., Bochkova M.S., Khramtsov P.V., Rayev M.B.
Prognosis of immune state following basic therapy and thymalin treatment in patients with severe COVID-19 infection
Kuznik B.I., Smolyakov Y.N., Shapovalov K.G., Tereshkov P.P., Konnov V.A., Chalisova N.I.
EFFECTS OF CARBOPLATIN WITH CUCURBIT[7]URIL ON SUBPOPULATION COMPOSITION AND PROLIFERATIVE ACTIVITY OF LYMPHOCYTES IN VITRO
Pashkina E.A., Aktanova A.A., Ermakov A.A., Knauer N.Y., Mirzaeva I.V., Kovalenko E.A.
Killer cell cluster immunity state in adult patients with common variable immunodeficiency
Prokopovich S. ., Novikova I.A.
THE ROLE OF PREGNANCY-SPECITIC GLYCOPROTEIN IN THE REGULATION OF PRODUCTION OF KEY CYTOKINES THAT DETERMINE BALANCE Th1 / Th2
Zamorina S.A., Litvinova L.S., Yurova K.A., Khaziakhmatova O.G., Timganova V.P., Bochkova M.S., Khramtsov P.V., Rayev M.B.
State of hyperglycemic and immunomodulator-treated peripheral blood lymphocytes
Gette I.F., Danilova I.G.
CD4+ T-LYMPHOCYTE FUNCTION IS VIOLATED IN HIV-INFECTED PATIENTS WITH DISCORDANT RESPONSE TO ANTIRETROVIRAL THERAPY
Korolevskaya L.B., Saidakova E.V.
COEXPRESSION OF IMMUNE CHECKPOINT MARKERS PD-1, PD-L1, TIM-3, AND LAG-3 IN CIRCULATING AND TUMOR-INFILTRATING T CELL POPULATIONS IN CERVICAL CANCER PATIENTS
Kurmyshkina O.V., Bogdanova A.A., Kovchur P.I., Volkova T.O.
DIFFERENTIATION OF T-CELLS UNDER PRIVACY PREGNANCY OF PREGNANCY IN WOMEN OF CHELYABINSK REGION
Baturina I.L., Loginova Y.V., Zotova M.A., Novozhenina V.S., Kokh E.V.
FEATURES OF T-LYMPHOCYTES SUBPOPULATIONS IN CHRONIC HERPETIC INFECTION
Knysh S.V., Malkov V.A., Shiraeva A.V., Baibarina E.V.
GM-CSF-INDUCED GRANULOCYTIC MYELOID REGULATORY CELLS ARE ACTIVATED BY BACTERIAL LIPOPOLYSACCHARIDE TO SUPPRESS HUMAN T-CELL RESPONSES
Gaponov A.M., Pisarev V.M., Tutelyan A.V.
IMMUNOHISTOCHEMICAL CHARACTERISTICS OF TUMOR-INFILTRATING T-LYMPHOCYTE SUBPOPULATIONS OF THE WARTHIN-LIKE VARIANT OF PAPILLARY THYROID CANCER
Bogolyubova A.V., Abrosimov A.Y., Selivanova L.S., Dvinskikh N.Y., Kuprash D.V., Belousov P.V.
Glucose uptake by CD4+Т cell subsets in HIV-infected patients receiving highly active antiretroviral therapy (haart)
Korolevskaya L.B., Saidakova E.V., Vlasova V.V., Shmagel K.V.
Spontaneous and stimulated CD25 expression on T-lymphocytes and the amount of regulatory T-cells in children with chronic hepatitis C
Pashnina I...
ASSESSMENT OF CD127⁻ AND CD95⁺ EXPRESSION AND GENETIC PROFILE OF WOMEN OF REPRODUCTIVE AGE EXPOSED TO PHENOL
Dolgikh O.V., Kazakova O.A., Krivtsov A.V.
DEVELOPMENT OF MODELS OF HUMAN MALIGNANT TUMORS FOR CELLULAR IMMUNOTHERAPY
Zlatnik E.Y., Maksimov A.Y., Goncharova A.S., Karnaukhov N.S.
Effect of melatonin include into original dermal film upon adaptive immunity in experimental thermal trauma
Osikov M.V., Simonyan E.V., Ageeva A.A., Nikushkina K.V.
HORIONIC GONADOTROPIN IN REGULATION OF THE FUNCTIONAL ACTIVITY OF T-REGULATORY LYMPHOCYTES
Zamorina S.A.
ANALYSIS OF THE APOPTOTIC DEATH INDICATORS OF LYMPHOCYTES AMONG THE PERSONS EXPOSED TO CHRONIC IRRADIATION
Blinova E.A., Akleyev A.A.
LYMPHOCYTE SUBPOPULATION PROFILE IN PATIENTS WITH METABOLIC SYNDROME AND IT’S CHANGE UNDER THE INFLUENCE OF ADIPOKINS IN EXPERIMENTAL CONDITIONS
Sumerkina V.A., Telesheva L.F., Golovneva E.S., Baturina I.L., Naimushina Y.V.
CONTRIBUTION OF DIFFERENT TYPES OF MELATONINE RECEPTORS TO HORMONE-DEPENDENT REGULATION OF T LYMPHOCYTES PRODUCING IL-17 (TH17) DIFFERENTIATION
Glebezdina N.S., Nekrasova I.V., Olina A.A., Sadykova G.K.
Immunotropic effect of medicinal plants with different microelemental composition
Ivanova E.V., Voronkova I.P., Bondarenko A.I., Tarenkova I.V.
THE REGULATION OF TREG DIFFERENTIATION BY ENDOGENOUS MELATONIN DURING PREGNANCY
Glebezdina N.S., Olina A.A., Nekrasova I.V., Kuklina E.M.
INFLUENCE OF DIFFERENT INTERFERON-GAMMA (IFN-γ) CONCENTRATIONS ON CELLS OF THE IMMUNE SYSTEM IN VITRO
Sitkovskaya A.O., Sagakyants A.B., Filippova S.Y., Mezhevova I.V., Bondarenko E.S., Statsenko K.G., Popova M.M.
Features of altered immune status in acute brain concussion
Norka A.O., Vorobyev S.V., Kuznetsova R.N., Serebriakova M.K., Kudryavtsev I.V., Kovalenko S.N.
DISTURBANCES OF BONE BLOCKS IN THE OSTEOSYNTHESIS SPINAL DEVICE OF EXTERNAL FIXATION POSSIBLE TO PREDICT
Berdyugin K.A.
Features of hapten specific sensitization and immune status in different student age groups
Dolgikh O.V., Dianova D.G.
THE ROLE OF B1 AND B2 LYMPHOCYTES IN THE FORMATION OF DIFFERENT VARIANTS OF RHEUMATOID ARTHRITIS
Sizyakina L.P., Kharitonova M.V.
Effects of beta-endorphin and dynorphin A on in vitro apoptosis in human peripheral blood lymphocytes
Yuzhaninova S.V., Gileva S.G.
New opportunities of immunocorrection in complex treatment of cervical cancer patients
Menshenina A.P., Zlatnik E.Y., Sagakyants A.B., Moiseenko T.I., Ushakova N.D., Frantsiyants E.M., Verenikina E.V., Chalabova T.G.
Features of peripheral blood B cell phenotype in patients with pressure ulcers
Borisov S.A., Savchenko A.A., Kasparov E.V., Fokin V.A., Matsenko M.V., Kudryavtsev I.V., Borisov A.G.
THE EFFECT OF LOCAL APPLICATION OF ERYTHROPOIETIN ON DEATH INDICATORS OF LYMPHOCYTES IN THE BLOOD IN THE DYNAMICS OF EXPERIMENTAL THERMAL INJURY
Osikov M.V., Simonyan E.V., Saedgalina O.T., Bivalkevich V.A.
COMPARATIVE CHARACTERISTICS OF THE SUBPOPULATION COMPOSITION OF LYMPHOCYTES AND HEAT SHOCK PROTEIN IN PATIENTS WITH VIBRATION DISEASE
Kurchevenko S.I., Bodienkova G.M., Lakhman O.L.
Expression of CD39 and CD73 ectonucleotidases in CD4+ lymphocyte populations in healthy children
Radygina T.V., Kuptsova D.G., Petrichuk S.V., Semikina E.L., Fisenko A.P.
Chronic immune activation reduces CD4+T cell susceptibility to IL-7 in HIV-infected patients that poorly respond to antiretroviral therapy
Saidakova E.V., Korolevskaya L.B., Shmagel K.V.
THE FEATURES OF IMMUNOLOGICAL REACTIVITY OF WOMEN YAMALO-NENETS AUTONOMOUS DISTRICT
Morozova O.S., Kabbani M.S.
ESTIMATION OF IMMUNOLOGICAL EFFICIENCY OF PEOPLE VACCINATED AGAINST ANTHRAX
Silkina M.V., Kartseva A.S., Kalmantaeva O.V., Rogozin M.M., Firstova V.V., Shemyakin I.G.
RECEPTOR FUNCTIONS OF SEMA4D IN THE CONTROL OF T-LYMPHOCYTE PROLIFERATION
Kuklina E.M.
Subpopulation structure of T-lymphocytes in children with diff erent activity of juvenile idiopathic arthritis
Pashnina I...
THE INDICES OF IMMUNITY AND THE CLINICAL COURSE OF POSTTRAUMATIC PERIOD IN PATIENTS WITH PENETRATING WOUNDS OF THE EYEBALL WHEN INCLUDED IN A COMPREHENSIVE TREATMENT OF THE DRUG BESTIM
Maracheva N.M., Marachev S.I.
COMPARISON OF THE EARLY IMMUNE RESPONSE OF MICE IMMUNIZED BY TULAREMIA VACCINE STRAIN AND ITS DERIVATIVES
Kartseva A.S., Silkina M.V., Kalmantaeva O.V., Mironova R.I., Firstova V.V., Pavlov V.M., Shemyakin I.G.
PHENOTYPING OF ANTIGEN-SPECIFIC CYTOTOXIC T-LYMPHOCYTES BY THE METHOD OF MULTICOLOR FLOW CYTOMETRY
Kuznetsova M.S., Lopatnikova J.A., Sennikov S.V.
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