IMMUNOHISTOCHEMICAL CHARACTERISTICS OF TUMOR-INFILTRATING T-LYMPHOCYTE SUBPOPULATIONS OF THE WARTHIN-LIKE VARIANT OF PAPILLARY THYROID CANCER

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Abstract

Tumor-infiltrating immune cells, in particular T-lymphocytes, can both stimulate and inhibit the tumor growth. Warthin-like variant of papillary thyroid cancer is a unique tumor characterized by an abnormally abundant immune infi ltration. We performed the analysis of the composition of T-cell subpopulations in the contexture of this type of cancer.

About the authors

A. V. Bogolyubova

Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences;
Educational Fund “Talent and Success”, Educational center “Sirius”

Author for correspondence.
Email: apollinariya.bogolyubova@gmail.com

junior staff scientist Laboratory of intracellular signaling in health and disease, 119991, Moscow, Vavilova str., 32;

staff scientist, Sochi

Russian Federation

A. Yu. Abrosimov

National Medical Research Center for Endocrinology;
National University of Science & Technology «MISIS»

Email: fake@neicon.ru

PhD, head of the department Department of Basic Pathology;

Laboratory «Physical methods, acousto-optical and laser devices for diagnosis and therapy of oncological diseases», 

Moscow

Russian Federation

L. S. Selivanova

Department of Basic Pathology, National Medical Research Center for Endocrinology

Email: fake@neicon.ru

PhD, senior staff scientist Department of Basic Pathology,

Moscow

Russian Federation

N. Yu. Dvinskikh

A. Tsyb Medical Radiological Research Center, Ministry of Health
of Russian Federation

Email: fake@neicon.ru
PhD, head of the Department of Pathology, Obninsk Russian Federation

D. V. Kuprash

Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences

Email: fake@neicon.ru

PhD, head of the Laboratory of intracellular signaling in health and disease,

Moscow

Russian Federation

P. V. Belousov

Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences;
National University of Science & Technology «MISIS»

Email: fake@neicon.ru

junior staff scientist Laboratory of intracellular signaling in health and disease;

Laboratory «Physical methods, acousto-optical and laser devices for diagnosis and therapy of oncological diseases»,

Moscow

Russian Federation

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Copyright (c) 2019 Bogolyubova A.V., Abrosimov A.Y., Selivanova L.S., Dvinskikh N.Y., Kuprash D.V., Belousov P.V.

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