IMMUNOTROPIC INFLUENCE OF RHODOCOCCUS-BIOSURFACTANT IN VIVO

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Abstract

Microbial biosurfactant complex Rhodococcus ruber IEGM 231 has immunoregulatory properties. It was established that the glycolipid complex and its dominant fraction of monoacyltrehalose exerted a depressing effect on innate and acquired immunity of laboratory mice with intraperitoneal and intramuscular injection.

About the authors

O. A. Kochina

Institute of ecology and genetics of microorganisms

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

M. S. Kuyukina

Institute of ecology and genetics of microorganisms; Perm State University

Email: noemail@neicon.ru
Russian Federation

I. B. Ivshina

Institute of ecology and genetics of microorganisms

Email: noemail@neicon.ru
Russian Federation

References

  1. Paulino B. N., Pessoa M. G., Mano M. C. R. Current status in biotechnological production and applications of glycolipid biosurfactants. Appl Microbiol Biotechnol. 2016, (100 (24)), 10265-10293.
  2. Shao Z. Trehalolipids. In: Biosurfactants from genes to applications. Soberon-Chavez G (ed), Springer-Verlag, Berlin 2011, 216.
  3. Куюкина М. С., Ившина И. Б., Гейн С. В., Баева Т. А., Черешнев В. А. In vitro иммуномодулирующая активность биосурфактантного гли-колипидного комплекса из Rhodococcus ruber. Бюллетень экспериментальной биологии и медицины. 2007, 144 (9), 301-305.

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Copyright (c) 2017 Kochina O.A., Kuyukina M.S., Ivshina I.B.

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