Email this article THE ROLE OF THE ENDOGENOUS OPIOID SYSTEM IN THE REGULATION OF ANTIBODY GENESIS DURING CHRONIC COLD STRESS
- Authors: Sharav’eva I.L.1, Gein S.V.1,2
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Affiliations:
- Institute of Ecology and Genetics of Microorganisms, UB RAS
- Perm State University
- Issue: Vol 22, No 2-2 (2019)
- Pages: 969-971
- Section: ORIGINAL ARTICLES
- Submitted: 29.07.2020
- Accepted: 29.07.2020
- Published: 15.07.2019
- URL: https://rusimmun.ru/jour/article/view/426
- DOI: https://doi.org/10.31857/S102872210006501-6
- ID: 426
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Abstract
It was established that under conditions of chronic cold stress in mice, a decrease in the absolute and relative amount of antibody-forming cells in the spleen was observed. The blockade of opiate receptors led to the abolition of oppression.
About the authors
I. L. Sharav’eva
Institute of Ecology and Genetics of Microorganisms, UB RAS
Author for correspondence.
Email: irin.sh@gmail.com
PhD, recercher of the laboratory of biochemistry of development of microorganisms,
Perm
Russian FederationS. V. Gein
Institute of Ecology and Genetics of Microorganisms, UB RAS;Perm State University
Email: fake@neicon.ru
doctor of medicine deputy director for research;
professor Department of microbiology and immunology,
Perm
Russian FederationReferences
- Vuong C., Van Uum S. H., O’Dell L. E., Lutfy K., Friedman T. C. The effects of opioids and opioid analogs on animal and human endocrine systems. Endocr Rev., 2010, 31(1), 98–132.
- Toubia T., Khalife T. The Endogenous opioid system: role and dysfunction caused by opioid therapy. Clin Obstet Gynecol., 2019, 62, 3–10.
- Kido K., Shindo Y., Toda S., Masaki E. Expression of β-endorphin in peripheral tissues after systemic administration of lipopolysaccharide as a model of endotoxic shock in mice. Ann Endocrinol, 2018, 18, 30095–7.
- Гейн С. В., Шаравьева И. Л. Влияние блокады опиатных рецепторов на антителогенез и пролиферативный ответ спленоцитов при стрессе. Экспериментальная и клиническая фармакология, 2013, 1, 30–34.
- Jerne N. K., Nordin A. A. Plaque formation in agar by single antibody-producing cells. Science, 1963, 140, 405.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).