ASSESSMENT OF HIGH LEVELS OF ANTIBODIES TO HERPES SIMPLEX VIRUS CLINICAL VALUE IN HEAD AND BACK PAIN OUTPATIENTS

Aim: to assess clinical value of antibodies to Herpes Simplex Virus (HSV) in outpatients with head and back pain. Cross sectional study included 45 female outpatients aged from 40 to 60. Two or more HSVinfec-tion exacerbations per year were registered in 25 persons (Group1) while 20 women had no exacerbation during previous year (Group 2). General practitioner and neurologist examination have been performed accompanied by IEA IgG anti-HSV type 1,2 antibodies assessment. Results: Group 1 showed 5-fold higher IgG anti-HSV antibodies level and post-herpetic neuralgia frequency then Group 2. High IgG anti-HSV antibodies level was associated with increased odds of HSV infection exacerbation (OR = 1.8; 95 % СШ 1.2-2.6).

простой герпес, иммуноглобулины класса G, антитела, обострение болезни, Herpes Simplex Virus, immunoglobulin G, antibodies, disease exacerbation