DYNAMICS OF CYTOKINE PRODUCTION OF BLOOD SERUM AND AMNIOTIC FLUID AT A THREAT OF PREGNANCY INTERRUPTION

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Abstract

The level of cytokines (TNF-α, TGF-β, IL-1β and IL-10) in serum and amniotic fluid medium be representative of the state of interleukin balance in gestational tissues, and its definition has a high informative value for judging the course of pregnancy and fetal development fetus.

About the authors

I. I. Krukier

Research Institute of Obstetrics and Pediatrics Rostov State Medical University

Author for correspondence.
Email: biochem@rniiap.ru

PhD, Leading Researcher of the Department of Biomedical Problems in Obstetrics, Gynecology and Pediatrics,

Rostov-on-Don

Russian Federation

L. L. Erdzhanyan

Research Institute of Obstetrics and Pediatrics Rostov State Medical University

Email: fake@neicon.ru

Junior Researcher of the Obstetric-Gynecological Department,

Rostov-on-Don

Russian Federation

V. V. Avrutskaya

Research Institute of Obstetrics and Pediatrics Rostov State Medical University

Email: fake@neicon.ru

MD, Associate Professor, Chief Researcher of the Obstetric-Gynecological Department,

Rostov-on-Don

Russian Federation

A. V. Rozhkov

FKUZ “Polyclinic № 1” FCS of Russia

Email: fake@neicon.ru

MD, Head of the Polyclinic,

Rostov-on-Don

Russian Federation

A. A. Nikashina

Research Institute of Obstetrics and Pediatrics Rostov State Medical University

Email: fake@neicon.ru

Ph.D., Researcher of the Department of Biomedical Problems in Obstetrics, Gynecology and Pediatrics,

Rostov-on-Don

Russian Federation

Yu. A. Petrov

Research Institute of Obstetrics and Pediatrics Rostov State Medical University

Email: fake@neicon.ru

MD, Professor, Head of the Department of Obstetrics and Gynecology No. 2,

Rostov-on-Don

Russian Federation

References

  1. Симбирцев А. С. Цитокины в патогенезе инфекционных и неинфекционных заболеваний человека. Медицинский академический журнал. 2013; 13(3):18–41.
  2. Акушерство. Национальное руководство. Краткое издание / Под.ред. Э. К. Айламазяна, В. Н. Серова, В. Е. Радзинского, Г. М. Савельевой. Москва, 2012.
  3. Крукиер И. И., Авруцкая В. В., Левкович М. А., Нарежная Е. В., Смолянинов Г. В., Ерджанян Л. Л., Никашина А. А. Особенности изменения биорегуляторов и органических кислот в сыворотке крови и амниотической жидкости женщин со спонтанными преждевременными родами //Вестник Российской академии медицинских наук. 2018. Т. 73. № 6. С. 361–367.

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Copyright (c) 2019 Krukier I.I., Erdzhanyan L.L., Avrutskaya V.V., Rozhkov A.V., Nikashina A.A., Petrov Y.A.

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