Email this article CHANGES IN PERIPHERAL BLOOD INDICATORS IN PATIENTS WITH PSORIASIS
- Authors: Nefed’eva J.1, Shishkova J.S.1, Raisovich Z.O.1,2
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Affiliations:
- Chelyabinsk State Medical University, Chelyabinsk, Russia
- State Budgetary Healthcare Institution "Chelyabinsk Regional Clinical Skin and Venereal Diseases Dispensary", Chelyabinsk
- Section: Forum Sochi 2025
- Submitted: 29.04.2025
- Accepted: 22.06.2025
- URL: https://rusimmun.ru/jour/article/view/17256
- DOI: https://doi.org/10.46235/1028-7221-1090-CIP
- ID: 17256
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Abstract
Abstract
The problem of widespread psoriasis is one of the most urgent due to its wide prevalence, lack of a single etiopathogenetic concept, diversity of clinical forms and systemic manifestations of the disease. The study of changes in the leukocyte formula of a complete blood count and biochemical parameters of peripheral blood in psoriasis has an important clinical and diagnostic value.
The purpose of the study was to study laboratory parameters of peripheral blood in patients with psoriasis who underwent inpatient treatment in the 24-hour department of the Chelyabinsk Regional Clinical Skin and Venereal Diseases Dispensary.
Materials and methods. Laboratory parameters of general and biochemical blood tests were studied in 750 patients with psoriasis at the Chelyabinsk Regional Clinical Skin and Venereal Diseases Dispensary.
Results. The study revealed an increase in the erythrocyte sedimentation rate in elderly patients with severe psoriasis. In middle-aged and elderly women and men with moderate psoriasis, dyslipidemia with increased levels of cholesterol and triglycerides in the peripheral blood was detected. In patients with psoriasis over 45 years of age with moderate course of the disease, an excess of total bilirubin was more often observed.
Conclusion. An increase in systemic inflammation markers C-reactive protein, ESR, dyslipidemia is observed in psoriatic disease.
About the authors
Julia Nefed’eva
Chelyabinsk State Medical University, Chelyabinsk, Russia
Email: women200681@mail.ru
ORCID iD: 0000-0002-8264-1068
MD, PhD, Associate Professor, Department of Dermatovenereology
Russian FederationJulia Sergeevna Shishkova
Chelyabinsk State Medical University, Chelyabinsk, Russia
Email: shishkova_yulia@mail.ru
MD, Professor, Department of Microbiology, Virology and Immunology
Russian Federation, г. Челябинск, ул. Воровского 64Ziganshin Oleg Raisovich
Chelyabinsk State Medical University, Chelyabinsk, Russia;State Budgetary Healthcare Institution "Chelyabinsk Regional Clinical Skin and Venereal Diseases Dispensary", Chelyabinsk
Author for correspondence.
Email: ziganshin_oleg@mail.ru
MD, Professor, Head of Department of Dermatovenereology
Russian Federation, Chelyabinsk, Russia, 454092, Yablochkina 24References
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