CLINICAL FEATURES OF THE COURSE OF ACUTE RESPIRATORY VIRAL INFECTION OF VARIOUS ETIOLOGY IN PATIENTS WITH ARTERIAL HYPERTENSION



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Abstract

AbstractAcute respiratory viral infection (ARVI) is one of the causes of global morbidity. Arterial hypertension (AH) is the most common chronic non-infectious disease, against which ARVI can occur. The aim of the study is to investigate the clinical features of ARVI of various etiologies (COVID-19, influenza, and unspecified) in patients with arterial hypertension. Material and methods. The retrospective, comparative study included 536 patients divided into three groups: ARVI unspecified (group 1) – 249 people; COVID-19 (group 2) – 250 patients; influenza (group 3) – 36 respondents. Each of the three groups included two subgroups: A – only ARVI (unspecified, COVID-19, influenza), B – ARVI (unspecified, COVID-19, influenza)+AG. Statistical data processing was carried out using STATISTICA 10.0 software packages. Results and discussion. The manifestations of intoxication and catarrhal syndrome occurred in patients of groups 1A and 1B, their severity was different. In respondents with ARVI and AH (group 1B), the course of ARVI differs in the following parameters: runny nose (χ2=4.3; p=0.040), sore throat (χ2=4.3; p=0.037), fever to febrile digits (χ =24.5; p=0.000). The clinical picture in patients with COVID-19+hypertension differed from patients with COVID-19 without hypertension in that more patients had loss of sense of smell (χ2=3.84; p=0.050), headaches (χ2=3.84; p=0.050), myalgia (χ2=4.38; p=0.036), sleep disorders (χ2=4.11; p=0.043), cough (χ2=4.18; p=0.041), prolonged febrile fever (U = 2.01; p=0.044) (χ2 =5.74; p=0.017). Patients with influenza and AH were more likely to report nasal congestion (χ2=9.93; p=0.002), cough (χ2=4.11; p=0.043), and fever (χ2=11.25; p=0.000), which lasted up to 8.5 days (U=2.59; p=0.023). Conclusion. For all patients, regardless of the genesis of ARVI in the presence of AH, febrile fever was more common and longer. The manifestations of intoxication and catarrhal syndrome in patients with influenza+AH are distinguished by the presence of complaints of nasal congestion, cough and sleep disorders. In COVID-19+AH – loss of smell, headache, myalgia, sleep disorders. Knowledge of the clinical features of the course of ARVI of various etiologies in patients with AH will allow for timely correction of treatment of both ARVI and AH at the early stages.

About the authors

Ekaterina Antipova

Federal State Budgetary Educational Institution of Higher Education “Omsk State Medical University” of the Ministry of Health of the Russian Federation, Omsk, Russia

Email: eantipova74@mail.ru

Federal State Budgetary Educational Institution of Higher Education Omsk State Medical University of the Ministry of Health of the Russian Federation, Department of Phthisiology, Pulmonology and Infectious Diseases, Assistant Professor of the Department

Russian Federation

Anna Mordyk

Federal State Budgetary Educational Institution of Higher Education “Omsk State Medical University” of the Ministry of Health of the Russian Federation, Omsk, Russia;
Federal State Budgetary Institution “National Medical Research Center for Phthisiopulmonology and Infectious Diseases” of the Ministry of Health of the Russian Federation, Moscow

Email: amordik@mail.ru

Doctor of Medical Sciences, Professor, Head of the Department of Phthisiology, Pulmonology, and Infectious Diseases

Russian Federation, 644099, Omsk, Lenina Street, 12

Natalya V. Bagisheva

Federal State Budgetary Educational Institution of Higher Education “Omsk State Medical University” of the Ministry of Health of the Russian Federation, Omsk, Russia

Email: ppi100@mail.ru

Doctor of Medical Sciences, Associate Professor of the Department of Polyclinic Medicine

Russian Federation, 644099, Omsk, Lenina Street, 12

Marina V. Moiseeva

Federal State Budgetary Educational Institution of Higher Education “Omsk State Medical University” of the Ministry of Health of the Russian Federation, Omsk, Russia

Email: lisnyak80@mail.ru

Candidate of Medical Sciences, Associate Professor

Russian Federation

Victoria V. Streltsova

Federal State Budgetary Educational Institution of Higher Education “Omsk State Medical University” of the Ministry of Health of the Russian Federation, Omsk, Russia

Author for correspondence.
Email: vstrl1611@gmail.com

Applicant.

Russian Federation

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