HIV INFECTION AND HIV/HCV CO-INFECTION PROBLEM
- Authors: Balmasova I.P.1,2, Malova E.S.2, Efratova E.P.3
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Affiliations:
- A.I. Evdokimov Moscow Univercity of Medcine & Dentistry
- Peoples‘ Friendship University of Russia
- Samara State Medical University
- Issue: Vol 22, No 2-1 (2019)
- Pages: 144-146
- Section: ORIGINAL ARTICLES
- Submitted: 04.04.2020
- Accepted: 04.04.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/25
- DOI: https://doi.org/10.31857/S102872210006430-8
- ID: 25
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Abstract
The patterns of coinfection, which extend to coinfection of HIV/HCV, make it expedient to test the hypothesis about the impact of the order of viral pathogens admission into host for the development of the infectious process. It was found that this factor has a significant impact on the course of liver fibrosis, the viral load of HIV and HCV, the state of the immune response. In cases where HIV infection develops before hepatitis C virus infection, liver fibrosis often takes a progressive course, the viral load of HIV is reduced, and HCV load increases, CD8+ T-lymphocytes and immunoregulatory index values become lower.
About the authors
I. P. Balmasova
A.I. Evdokimov Moscow Univercity of Medcine & Dentistry;Peoples‘ Friendship University of Russia
Author for correspondence.
Email: iri.balm@mail.ru
MD, professor, Head of the Laboratory of the Pathogenesis and Treatment of Infectious Diseases;
Professor of Allergology and Immunology Department,
Moscow
Russian FederationE. S. Malova
Peoples‘ Friendship University of Russia
Email: fake@neicon.ru
MD, Professor of Allergology and Immunology Department,
Moscow
Russian FederationE. P. Efratova
Samara State Medical University
Email: fake@neicon.ru
ordinator of Infectious Diseases Department,
Samara
Russian FederationReferences
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