GENERATION AND CHARACTERIZATION OF RECOMBINANT ANTIBODY AGAINST THE COMPLEMENT C5a ANAPHYLATOXIN
- Authors: Vasilishina A.A.1, Demyanov A.V.1, Monahova V.S.1, Zhakhov A.V.1, Trofimov A.V.1, Denisenko E.S.1, Nekrasova K.A.1, Rodin S.V.1, Simbirtsev A.S.1, Ischenko A.M.1
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Affiliations:
- State Research Institute of Highly Pure Biopreparations
- Issue: Vol 22, No 2-2 (2019)
- Pages: 728-730
- Section: ORIGINAL ARTICLES
- Submitted: 03.06.2020
- Accepted: 03.06.2020
- Published: 15.07.2019
- URL: https://rusimmun.ru/jour/article/view/281
- DOI: https://doi.org/10.31857/S102872210006722-9
- ID: 281
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About the authors
A. A. Vasilishina
State Research Institute of Highly Pure Biopreparations
Author for correspondence.
Email: a.a.vasilishna@hpb.spb.ru
MD, Biologist of Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. V. Demyanov
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
MD, Head of Laboratory of Immunopharmacology,
Saint Petersburg
Russian FederationV. S. Monahova
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
Biologist, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. V. Zhakhov
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
Leading Researcher, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. V. Trofimov
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
Group Leader, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationE. S. Denisenko
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
Project Manager,
Saint Petersburg
Russian FederationK. A. Nekrasova
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
Deputy Head of R&D Department,
Saint Petersburg
Russian FederationS. V. Rodin
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
Group Leader, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. S. Simbirtsev
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
RAS Corresponding Member, DMedSci, Professor, Scientific Supervisоr,
Saint Petersburg
Russian FederationA. M. Ischenko
State Research Institute of Highly Pure Biopreparations
Email: fake@neicon.ru
PhD, Head of Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationReferences
- Chunguang Yan, Hongwei Gao. New insights for C5a and C5a receptors in sepsis. Front Immunol. 2012, 5, 197.
- Aird W. C. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood. 2003, 101, 3765–3777.
- Peter A. Ward Role of C5 Activation Products in Sepsis. The Scientific World Journal. 2010, 10, 2395– 24022010.