THE FEATURES OF IL-4 AND IL-10 PRODUCTION IN UPPER GASTROINTESTINAL INFLAMMATORY DISEASES

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Abstract

The peculiarities of the IL-4 and IL-10 production have been studied in patients with upper gastrointestinal inflammatory diseases. It has been revealed that the serum level of these cytokines depends on presence or absence of allergic diseases and H.pyloriinfection.

About the authors

N. S. Iraklionova

Volgograd State Medical University

Author for correspondence.
Email: ins2904@rambler.ru

Professor’s assistant of Immunology and Allergology Department,

Volgograd

Russian Federation

E. B. Belan

Volgograd State Medical University

Email: fake@neicon.ru

MD, Professor, Head of Immunology and Allergology Department,

Volgograd

Russian Federation

S. V. Turkina

Volgograd State Medical University

Email: fake@neicon.ru

MD, Professor of Internal Diseases for Pediatric and Dental Faculties,

Volgograd

Russian Federation

E. L. Rudobaba

Volgograd State Medical University

Email: fake@neicon.ru

Professor’s assistant of Immunology and Allergology Department,

Volgograd

Russian Federation

References

  1. Караева В. Ю. Частота кровотечений при эрозивно-язвенных поражениях верхних отделов пищеварительного тракта у детей. Экспериментальная и клиническая гастроэнтерология. 2013, 1, 15–19.
  2. Faith A., Singh N., Farooque S., Dimeloe S., Richards D. F., Lu H., Roberts D., Chevretton E., Lee T. H., Corrigan C. J., Hawrylowicz C. M. T cells producing the anti-inflammatory cytokine IL-10 regulate allergenspecifi c Th2 responses in human airways. Allergy. 2012, 67(8), 1007–1013.
  3. Hussain K., Letley D. P., Greenaway A. B., Kenefeck R., Winter J. A., Tomlinson W., Rhead J., Staples E., Kaneko K., Atherton J. C., Robinson K. Helicobacter pylori-mediated protection from allergy is associated with IL-10-secreting peripheral blood regulatory T-cells. Frontiers in Immunology. 2016, 7, 1–15.

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Copyright (c) 2019 Iraklionova N.S., Belan E.B., Turkina S.V., Rudobaba E.L.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
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