PREVALENCE OF ANTINUCLEAR ANTIBODIES IN HEALTHY CHILDREN AND ADULTS

Cover Page


Cite item

Full Text

Abstract

Healthy donors (n=100) of 21–59 years old and healthy children (n=55) of 2–17 years old were examined. Antinuclear antibodies were determined by indirect immunofluorescence assay. It was found that 7 adults (7%) and 10 children (18%) had diagnostic titers of antinuclear antibodies detected by indirect immunofluorescence assay. In healthy children and adults homogeneous and speckled fluorescence patterns were observed more often.

About the authors

I. M. Krivolapova

Regional Child’s Clinical Hospital № 1;
Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences

Author for correspondence.
Email: krivolapovaim@mis66.ru

Biologist, Clinical Diagnostic Laboratory;

Junior Research Associate, Laboratory of Immunology of Inflammation, 

Yekaterinburg

Russian Federation

I. A. Pashnina

Regional Child’s Clinical Hospital № 1;
Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences

Email: fake@neicon.ru

PhD, Head of the laboratory, Clinical and diagnostic laboratory;

Senior Research Associate, Laboratory of Immunology of Inflammation,

Yekaterinburg

Russian Federation

V. A. Chereshnev

Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences

Email: fake@neicon.ru

PhD, Professor, Full Member, Russian Academy of Sciences, Main Research Associate, 

Yekaterinburg

Russian Federation

References

  1. Saton M., Chan E. K. L., Ho L. A., Rose K. M., Parks Ch. G., Cohn R. D., Jusko T. A., Walker N. J., Germolec D. R., Whitt I. Z., Crockett P. W., Pauley B. A., Chan J. Y. F., Ross S. J., Birnbaum L. S., Zeldin D. C., Miller F. W. Prevalence and Sociodemographic Correlates of Antinuclear Antibodies In the United States. Arthritis Rheum. 2012, 64; 7, 2319–2327.
  2. Cacciapaglia F., Arcarese L., Rigon A., Vadacca M., Valorani M. G., Pozzilli P., Afeltra A. Antinuclear antibodies prevalence in Filipinos migrated to Italy. Eur. Rev. Med. Pharmacol. Sci. 2008, 12; 4, 267–270.
  3. Wananukul S., Voramethkul W., Kaewopas Y., Orrawadee H. Prevalence of positive antinuclear antibodies in healthy children. Asian pacific journal of allergy and immunology. 2005, 23, 153–157.
  4. Allen R.C., Dewez P., Stuart L. Gatenby P. A., Sturgess A. Antinuclear antibodies using HEp-2 cells in normal children and in children with common infections. J. Paediatr. Child. Health. 1991, 27; 1, 39–42.
  5. Пашнина, И.А, Плотникова И. А., Криволапова И. М., Цегельная В. П., Тузанкина И. А., Каракина М. Л., Семишева И. А. Признаки иммунопатологических процессов у детей, проживающих на территории с высокой техногенной нагрузкой. Известия Самарского научного центра Российской академии наук. 2013, 15; 3(6), 1904–1907.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2019 Krivolapova I.M., Pashnina I.A., Chereshnev V.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № 77 - 11525 от 04.01.2002.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies