CHARACTERIZATION OF HUMAN PAPILLOMAVIRUS VACCINES: THE WORLD EXPERIENCE



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Abstract

Persistence of high-risk human papillomavirus (HPV) genotypes is the leading cause of cervical cancer, as well as anogenital and oropharyngeal cancers. This article focuses on analysis of the global use of the licensed HPV vaccines, given the introduction of HPV vaccination into national immunization programs of many countries. All vaccines are safe, immunogenic and effective in population usage, with the most frequent adverse event being injection-site reactions.

About the authors

D. V. Gorenkov

The Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation

Author for correspondence.
Email: fake@neicon.ru

Category 1 Expert,

Moscow

Russian Federation

T. N. Nikitina

The Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation

Email: fake@neicon.ru

PhD, Main Expert, 

Moscow

Russian Federation

A. R. Volgin

The Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation

Email: fake@neicon.ru

PhD, Deputy Director of Centre for Evaluation and Control of MIBPs,

Moscow

Russian Federation

V. I. Klimov

The Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation

Email: fake@neicon.ru

PhD, Deputy Director of Centre for Planning and Coordination of Scientific Activities,

Moscow

 

Russian Federation

References

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  3. Brotherton J. M. L, Bloem P. N., Population-based HPV vaccination programmes are safe and eff ective: 2017 update and the impetus for…, Best Practice & Research Clinical Obstetrics and Gynaecology (2017), http://dx.doi.org/10.1016/j.bpobgyn.2017.08.010
  4. Chaturvedi A. K., Graubard B. I., Broutian T., Pickard R. K. L, Tong Z. Y., Xiao W., Kahle L., Gillison M. L. Eff ect of Prophylactic Human Papillomavirus (HPV) Vaccination on Oral HPV Infections Among Young Adults in the United States. J Clin Oncol. 2018;36(3):262. Epub 2017 Nov 28.
  5. Phillips A., Patel C., Pillsbury A. et al. Safety of Human Papillomavirus Vaccines: An Updated Review. Drug Saf. 2018;41:329. https://doi.org/10.1007/s40264-017-0625-z

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Copyright (c) 2019 Gorenkov D.V., Nikitina T.N., Volgin A.R., Klimov V.I.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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