Email this article INFLUENCE OF THE BLOCKADE OF OPIOID RECEPTORS ON HUMORAL IMMUNITY IN MALE AND FEMALE MICE UNDER IMMOBILIZATION STRESS
- Authors: Gein S.V.1,2, Sharavieva I.A.1, Tendrykova S.P.1,2
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Affiliations:
- Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences
- Perm State University
- Issue: Vol 20, No 2 (2017)
- Pages: 114-116
- Section: Articles
- Submitted: 22.10.2020
- Published: 15.04.2017
- URL: https://rusimmun.ru/jour/article/view/596
- ID: 596
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Abstract
It has been established that, both in females and in males, 6 h of immobilization resulted in a pronounced suppression of the amount of PFC in the spleen. Preliminary blockade of opiate receptors led to the abolition of the effect of stress in both males and females. However, in males, the administration of one naloxone had no effect on the number of PFC, while in females, naloxone inhibited the formation of PFC by both relative and absolute indices.
Keywords
About the authors
S. V. Gein
Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences; Perm State University
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
I. A. Sharavieva
Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences
Email: noemail@neicon.ru
Russian Federation
S. P. Tendrykova
Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences; Perm State University
Email: noemail@neicon.ru
Russian Federation
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Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).