PREVALENCE OF ANTINUCLEAR ANTIBODY IN CHILDREN WITH REACTIVE ARTHRITIS
- Authors: Krivolapova I.M.1,2, Pashnina I.A.1,2, Chereshnev V.A.2
-
Affiliations:
- Regional Child's Clinical Hospital № 1
- Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
- Issue: Vol 20, No 3 (2017)
- Pages: 398-400
- Section: Articles
- Submitted: 22.10.2020
- Published: 15.07.2017
- URL: https://rusimmun.ru/jour/article/view/700
- ID: 700
Cite item
Full Text
Abstract
Children with reactive arthritis (n=26) of 2-17 years old were examinated. Antinuclear antibodies were determined by indirect immunofluorescence assay, antibodies to extractable nuclear antigens were defined by ELISA. It was found that 12 patients (46 %) with reactive arthritis had diagnostic titers of antinuclear antibodies detected by indirect immunofluorescence assay. Homogeneous and speckled fluorescence patterns were observed in patients with reactive arthritis. The prevalence of antibodies to extractable nuclear antigens in children with reactive arthritis was low (8 %).
About the authors
I. M. Krivolapova
Regional Child's Clinical Hospital № 1; Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
I. A. Pashnina
Regional Child's Clinical Hospital № 1; Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
Email: noemail@neicon.ru
Russian Federation
V. A. Chereshnev
Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
Email: noemail@neicon.ru
Russian Federation
References
- Сиротко О. В. Актуальные вопросы дифференциальной диагностики ревматоидного и реактивного артритов. Вестник ВГМА 2010, том 9, 4, 75-84.
- Пашнина И. А., Криволапова И. М., Козло ва Е. С., Скоробогатова О. В., Тузанкина И. А., Черешнев В. А. Аутоантитела при ювенильных артритах у детей. Российский иммунологический журнал 2013, том 7(16), 4, 437-444.
- Алексеева Е. И., Чистякова Е. Г. Реактивный артрит. В кн.: Педиатрия: национальное руководство краткое издание. ГЭОТАР-Медиа, Москва 2014,177-196.
- Malleson P. N., Sailer M., Machinnon M. J. Useful-lness of antinuclear antibody testing to screen for rheumatic diseases. Archives of Disease in Childhood. 1997, 77, 299-304.
- Лапин С. В., Тотолян А. А. Иммунологическая лабораторная диагностика аутоиммунных заболеваний. Человек, Санкт-Петербург 2010, 272.