RELATIONSHIP SERUM LEVELS AND GENE POLYMORPHISMS OF IL-1a, IL-1RA WITH EFFICIENCY OF IN VITRO FERTILIZATION (IVF)
- Authors: Lapshtaeva A.V.1, Radaeva O.A.1, Novicova L.V.1, Efremov I.A.2
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Affiliations:
- Ogarev Mordovia State University
- Institute of biochemical physics of N. M. Emanuel Russian Academy of Sciences
- Issue: Vol 20, No 3 (2017)
- Pages: 402-404
- Section: Articles
- Submitted: 22.10.2020
- Published: 15.07.2017
- URL: https://rusimmun.ru/jour/article/view/702
- ID: 702
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Abstract
Women with tubal peritoneal infertility with an effective IVF had concentrations of IL-1a, IL-1ra in serum lower that women ineffective IVF. Genotype T/T gene IL-1a rs1800587 5'UTR area of the gene is associated with approach of pregnancy as a result of IVF (OR = 85,3, 95 %CI: 10,6-687, p<0,05).
About the authors
A. V. Lapshtaeva
Ogarev Mordovia State University
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
O. A. Radaeva
Ogarev Mordovia State University
Email: noemail@neicon.ru
Russian Federation
L. V. Novicova
Ogarev Mordovia State University
Email: noemail@neicon.ru
Russian Federation
I. A. Efremov
Institute of biochemical physics of N. M. Emanuel Russian Academy of Sciences
Email: noemail@neicon.ru
Russian Federation
References
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