PHENOMENON OF IMMUNOLOGICAL MEMORY DURING PREGNANCY

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Abstract

In preterm delivery both in the 1and in the 3 trimesters of pregnancy there was an elevated level of ef-fectory memory cells in the subset of cytotoxic T lymphocytes. Thus, the preterm delivery was associated with the enhancement of CD8+ lymphocytes differentiation towards terminal stages.

About the authors

L. V. Misharina

Federal State Budget Establishment Ivanovo's Scientific Research Institute of Maternity and Childhood by V. N. Gorodkov of Ministry of Health Care of Russian Federation

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

N. Yu. Sotnikova

Federal State Budget Establishment Ivanovo's Scientific Research Institute of Maternity and Childhood by V. N. Gorodkov of Ministry of Health Care of Russian Federation

Email: noemail@neicon.ru
Russian Federation

A. V. Kudryashova

Federal State Budget Establishment Ivanovo's Scientific Research Institute of Maternity and Childhood by V. N. Gorodkov of Ministry of Health Care of Russian Federation

Email: noemail@neicon.ru
Russian Federation

I. A. Vasin

Federal State Budget Establishment Ivanovo's Scientific Research Institute of Maternity and Childhood by V. N. Gorodkov of Ministry of Health Care of Russian Federation

Email: noemail@neicon.ru
Russian Federation

N. Yu. Borzova

Federal State Budget Establishment Ivanovo's Scientific Research Institute of Maternity and Childhood by V. N. Gorodkov of Ministry of Health Care of Russian Federation

Email: noemail@neicon.ru
Russian Federation

References

  1. Germain S. J., Sacks G. P., Sooranna S. R., Sargent I. L., Redman X. W. Systemic inflammatory priming in normal pregnancy and pre-eclampsia: the role of circulating syncytiotrophoblast microparticles. J. Immunol. 2007, 178, 5949-5956.
  2. Rusterholz C., Messerli M., Hoesli I., Hahn S. Placental microparticles, DNA and RNA in preeclampsia. Hypertens. Pregnany 2011, 30, 364-375.
  3. Кадырова Л. В., Сотникова Н. Ю., Кудряшова А. В. Динамика содержания наивных Т-клеток при неосложненной беременности Российский иммунологический журнал 2014, 8 (17), 1, 54-60.
  4. Кудряшова А. В., Кадырова Л. В. Дифференци-ровка CD8+ клеток памяти при беременности. Российский иммунологический журнал 2014, 8 (17), 1, 79-82.
  5. Кадырова Л. В., Борзова Н. Ю., Иваненкова Н. И. Особенности дифференцировки Т-лимфоцитов при невынашивании в ранние сроки гестации. Российский иммунологический журнал 2013, 7(16), 2-3, 275.

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Copyright (c) 2017 Misharina L.V., Sotnikova N.Y., Kudryashova A.V., Vasin I.A., Borzova N.Y.

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