SPONTANEOUS AND PHYTOGEMAGGLUTININ-STIMULATED EXPRESSION OF ACTIVATION MARKERS OD25, OD38, OD69 ON T-LYMPHOCYTES IN CHILDREN WITH DIFFERENT PATHOLOGY

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Abstract

Children with systemic lupus erithematosus, juvenile arthritis, reactive arthritis, chronicle hepatitis C and conditionally healthy children were investigated. Spontaneous number of СD3+СD25+ in children with hepatitis and number of СD3+СD69+ in patients with rheumatic diseases were similar to the control, after stimulation by phytogemagglutinin the amount of these subpopulations was less, then in healthy children.

About the authors

I. A. Pashnina

Regional Children's Clinical Hospital № 1, Institute of Immunology and Physiology, Urals Branch of the Russian Acad. Sci

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

References

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  4. Bahri R., Bollinger A., Bollinger T., Orinska Z., Bulfone-Paus S. Ectonucleotidase СD38 Demarcates Regulatory, Memory-Like СD8+ T Cells with IFN-y-Mediated Suppressor Activities. PLoS ONE, 2012, 7(9), http://www.ncbi.nlm.nih.gov/pmc/ar-ticles/PMC 3444472/
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