TO THE QUESTION OF DETECTION OF HEMOPHAGOCYTIC MACROPHAGES IN PERIPHERAL BLOOD OF NEWBORNS WITH THE MULTIPLE ORGAN DYSFUNCTION SYNDROME

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Abstract

The phenomenon of detection of hemophagocytic macrophages in newborns with multiple organ dysfunction syndrome (MODS) was studied. It has been shown that detection of hemophagocytic macrophages in peripheral blood takes place in newborns with severe manifestations of MODS and is a prog-nostically unfavorable sign.

About the authors

E. N. Serebrjakova

South Ural State Medical University

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

D. K. Volosnikov

South Ural State Medical University

Email: noemail@neicon.ru
Russian Federation

I. A. Beljaeva

National Scientific and Practical Center for Children's Health

Email: noemail@neicon.ru
Russian Federation

A. L. Ryzhkova

Chelyabinsk Regional Children's Clinical Hospital

Email: noemail@neicon.ru
Russian Federation

A. V. Sabirova

South Ural State Medical University

Email: noemail@neicon.ru
Russian Federation

References

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  2. Bestati N. Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter study. N. Bestati, S. Le-teurtre, A. Duhamel et al. Crit Care. 2010. Vol. 14, № 6. P. R 202.
  3. An G. Toward computational identification of multiscale “tipping points” in acute inflammation and multiple organ failure. G. An, G. Nieman, Y. Vodovotz. Ann Biomed Eng. 2012. Vol. 40, № 11. P. 2414-2424.
  4. Amos R. J. Observations on the haemopoietic response to critical illness. R. J. Amos, M. Deane, C. Ferguson et al. J. Clin Pathol. 1990. Vol. 43, № 10. P. 850-856.
  5. Kuwata K., Peripheral hemophagocytosis: аn early indicator of advanced systemic inflammatory response syndrome/hemophagocytic syndrome. K. Kuwata, S. Yamada, E. Kinuwaki et al. Shock. 2006. Vol. 25 № 4. Р. 344-350.

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Copyright (c) 2017 Serebrjakova E.N., Volosnikov D.K., Beljaeva I.A., Ryzhkova A.L., Sabirova A.V.

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