Email this article DINAMYCS OF HUMORAL IMMUNITY INDICATORS IN PATIENTS WITH ASEPTIC NECROSIS OF THE FEMORAL HEAD
- Authors: Chekushkin A.V.1, Safronov A.A.1, Safronof A.A.1, Matiyash A.M.1
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Affiliations:
- SEIHPE Orenburg State Medical University, Ministry of Health of Russia
- Issue: Vol 20, No 3 (2017)
- Pages: 555-557
- Section: Articles
- Submitted: 22.10.2020
- Published: 15.07.2017
- URL: https://rusimmun.ru/jour/article/view/766
- ID: 766
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Abstract
The level of B-lymphocytes, the major classes of Ig, circulating immune complexes(CIC) in blood of patients with aseptic necrosis of the femoral head (ANFH) before and after(in a year) total joint replacement surgery has been investigated. A significant reduction of initially high levels of IgG, CIC and b-lymphocytes after joint replacement is determined. The levels of IgG in the blood of patients with ANFH are considered as markers of the effective treatment.
About the authors
A. V. Chekushkin
SEIHPE Orenburg State Medical University, Ministry of Health of Russia
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
A. A. Safronov
SEIHPE Orenburg State Medical University, Ministry of Health of Russia
Email: noemail@neicon.ru
Russian Federation
Al. A. Safronof
SEIHPE Orenburg State Medical University, Ministry of Health of Russia
Email: noemail@neicon.ru
Russian Federation
A. M. Matiyash
SEIHPE Orenburg State Medical University, Ministry of Health of Russia
Email: noemail@neicon.ru
Russian Federation
References
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- Osteoimmunology: interplay between the immune system and bone metabolism / M. Walsh, N. Kim, Y. Kadono et al. //Ann. Rev. Immunol.- 2006.- V. 24.- C. 33-63.
- Immune complexes regulate bone metabolism through FcRγ signalling / T. Negishi-Koga, H. J. Gober, E. Sumiya et al. // Nat. Commun. - 2015. - V.31. doi: 10.1038/ncomms7637.
- Chen G. Y. Sterile infl ammation: sensing and reacting to damage / G. Y. Chen, G. Nunez // Nature Reviews Immunology- 2010. - V. 10, N 12. - P. 826-837.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).