CYTOKINES OF ADAPTIVE IMMUNITY IN THE PATHOGENESIS OF MULTIPLE SCLEROSIS

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Abstract

The review presents the publications mainly of the previous 5–7 years concerned to the production of adaptive immunity cytokines in multiple sclerosis clinical picture. There is discussed the possible pathogenetic value of cytokines produced by diff erent T-lymphocyte subpopulations: Th1, Th17, Th9, Th22, Th2 and Treg.

About the authors

G. F. Zheleznikova

Research Institute of Children Infections of the Federal Medico-Biological Agency of Russia

Author for correspondence.
Email: zheleznikova.galina@gmail.com

MD, PhD, Professor, Senior Research Associate of the Department of Clinical Laboratory Diagnostic

197022 Saint Petersburg, ul. Prof. Popova 9

Russian Federation

N. V. Skripchenko

Research Institute of Children Infections of the Federal Medico-Biological Agency of Russia; Saint-Petersburg State Pediatric Medical University

Email: fake@neicon.ru

Doctor of Medical Science, Professor, Vice-Director for Scientific Work

Saint Petersburg

Russian Federation

L. A. Alekseeva

Research Institute of Children Infections of the Federal Medico-Biological Agency of Russia

Email: fake@neicon.ru

PhD, MD (Biology), Leading Research Associate of the Department of Clinical Laboratory Diagnostic

Saint Petersburg

Russian Federation

E. Yu. Skripchenko

Saint-Petersburg State Pediatric Medical University; Federal State Budgetary Institution “Institute of Human Brain named after N. P. Bekhtereva, Russian Academy of Sciences”

Email: fake@neicon.ru

PhD, Head of Children’s Neurologic Department

Saint Petersburg

Russian Federation

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Copyright (c) 2017 Zheleznikova G.F., Skripchenko N.V., Alekseeva L.A., Skripchenko E.Y.

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