Email this article IMMUNE ASPECTS OF CANCER DEVELOPMENT
- Authors: Karmakova T.A.1
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Affiliations:
- P. A. Hertsen Moscow Oncology Research Institute – the branch of National Medical Research Radiological Center
- Issue: Vol 22, No 2-1 (2019)
- Pages: 296-298
- Section: ORIGINAL ARTICLES
- Submitted: 18.04.2020
- Accepted: 18.04.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/127
- DOI: https://doi.org/10.31857/S102872210006606-1
- ID: 127
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Abstract
Local and systemic immune responses are involved in the development of the malignant tumor at all stages of the process, from the appearance of transformed cellsto the clinical progression of the disease. The review includes the main provision of the modern concepts of oncogenesis, antitumor immune surveillance, immunoediting and the role of tumor-promoting chronic infl ammation.
Keywords
About the authors
T. A. Karmakova
P. A. Hertsen Moscow Oncology Research Institute – the branch of National Medical Research Radiological Center
Author for correspondence.
Email: kalmar123@yandex.ru
PhD, Leading Researcher, Department of Modifi ers and Protective Agents for Anticancer therapy,
Moscow
Russian FederationReferences
- Hanahan D., Weinberg R. A. Hallmarks of cancer: the next generation. Cell. 2011, 144(5), 646–674.
- Gonzalez H., Hagerling C., Werb Z. Roles of the immune system in cancer: from tumor initiation to metastatic progression. Genes Dev. 2018, 32, 1267–1284.
- Mittal D., Gubin M. M., Schreiber R. D., Smyth M. J. New insights into cancer immunoediting and its three component phases – elimination, equilibrium and escape. Curr Opin Immunol. 2014, 27, 16–25.
- Bottazzi B., Riboli E., Mantovani A. Aging, inflammation and cancer. SeminImmunol. 2018, 40, 74–82.
- D’Errico G., Machado H. L., Sainz B. Jr. A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bullet. Clin Trans Med. 2017, 6, 3
- Li Z., Song W., Rubinstein M., Liu D. Recent updates in cancer immunotherapy: a comprehensive review and perspective of the 2018 China Cancer Immunotherapy Workshop in Beijing. J Hematol Oncol. 2018, 11, 142.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).