IMMUNE DISTURBANCES AT THE LOCAL LEVEL IN CHRONIC ENDOMETRITIS; IMMUNE REHABILITATION

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Abstract

42 patients of reproductive age with a verifi ed diagnosis of chronic endometritis in the stage of incomplete remission were divided into 3 groups: the control group, receiving complex standard treatment and the main ones, where pharmacotherapy was supplemented with the administration of Gepon and Cytofl avin or a course of magneto-infrared laser therapy. Initially, an increase in the level of pro-infl ammatory and regulatory cytokines, activation of the complement system, an imbalance in the content of anti-infl ammatory cytokines, regulators of the complement system, a decrease in the sIgA level was established at the local level. The lack of eff ectiveness of the use of complex standard treatment in the correction of immune disorders was determined. The use of Gepon and Cytofl avin or magneto-infrared laser therapy eff ectively corrects disturbed parameters of the immune status.

About the authors

A. A. Konoplya

Kursk State Medical University

Author for correspondence.
Email: kanabis03101980@yandex.ru

MD, PhD, associate professor of obstetrics and gynecology department of Education Faculty,

Kursk

Russian Federation

S. A. Gavrish

Kursk State Medical University;
«Health Center»

Email: fake@neicon.ru

PhD student of obstetrics and gynecology department of Education Faculty;

obstetrician-gynecologist, 

Kursk

Russian Federation

Zh. P. Omasharifa

Kursk State Medical University

Email: fake@neicon.ru

assistant lecture of obstetrics and gynecology department of Education Faculty,

Kursk

Russian Federation

References

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  2. Кулаков В. И., Шуршалина А. В. Хронический эндометрит как причина нарушения репродуктивной функции // Гинекология. – 2012. – Т. 14, № 4. – С. 16–18.
  3. Сухих Г. Т., Шуршалина А. В. Хронический эндометрит: руководство. – М.: ГЭОТАР-Медиа, 2013. – 64 с.
  4. Конопля А. А., Гавриш С. А., Омашарифа Ж. П., Гаврилюк В. П., Конопля А. И. Иммунология бесплодия трубного генеза // Ученые записки Орловского государственного университета. Научный журнал. – 2014. – Т. 7, № 63. – С. 55–56.

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Copyright (c) 2019 Konoplya A.A., Gavrish S.A., Omasharifa Z.P.

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