Email this article DETERMINATION OF THE FREQUENCIES OF IL17A AND IL17F GENE POLYMORPHISMS IN WOMEN WITH MISCARRIAGE
- Authors: Loginova Y.V.1, Abramovskikh O.S.1, Nikonova T.I.1
-
Affiliations:
- Federal state budgetary educational institution of higher professional education “South Ural state medical University” Ministry of healthcare of the Russian Federation
- Issue: Vol 22, No 2-1 (2019)
- Pages: 377-379
- Section: ORIGINAL ARTICLES
- Submitted: 04.05.2020
- Accepted: 04.05.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/154
- DOI: https://doi.org/10.31857/S102872210006633-1
- ID: 154
Cite item
Full Text
Abstract
The paper presents the results of the analysis of the frequency distribution of alleles and genotypes of polymorphic sites rs2275913 of gene IL17A and rs763780 of gene IL17F in women with miscarriage. Statistically signifi cant differences in the distribution of alleles and genotypes of oligonucleotide polymorphisms rs2275913 of gene IL17A and of gene IL17F in women with miscarriage in comparison with a group of conditionally healthy women with two or more successful pregnancies paired with the same partner have not been identified.
About the authors
Y. V. Loginova
Federal state budgetary educational institution of higher professional education “South Ural state medical University” Ministry of healthcare of the Russian Federation
Author for correspondence.
Email: clinlab74@mail.ru
Junior Researcher of Research Institute of Immunology,
Chelyabinsk
Russian FederationO. S. Abramovskikh
Federal state budgetary educational institution of higher professional education “South Ural state medical University” Ministry of healthcare of the Russian Federation
Email: fake@neicon.ru
MD, Professor of the Department of Microbiology, Virology, Immunology and Clinical Laboratory Diagnostics,
Chelyabinsk
Russian FederationT. I. Nikonova
Federal state budgetary educational institution of higher professional education “South Ural state medical University” Ministry of healthcare of the Russian Federation
Email: fake@neicon.ru
senior laboratory assistant of Research Institute of Immunology,
Chelyabinsk
Russian FederationReferences
- Ghaebi M., Nouri M., Ghasemzadeh A., Farzadi L., Jadidi-Niaragh F., Ahmadi M., Yousefi M. Immune regulatory network in successful pregnancy and reproductive failures. Biomed. Pharmacother. 2017, 88, 61–73.
- Логинова Ю. В.. Абрамовских О. С. Анализ субпопуляционного состава Th-лимфоцитов в периферической крови у женщин с невынашиванием беременности. Российский иммунологический журнал. 2018, 12(21), 354–357.
- Najafi S., Hadinedoushan H., Eslami G., Afl atoonian A. Association of IL-17A and IL-17 F gene polymorphisms with recurrent pregnancy loss in Iranian women. J. Assist. Reprod. Genet. 2014, 31, 1491–1496.
- Питиримова Л. Н., Загороднева Е. А., Гумилевский Б. Ю. Особенности аллельного полиморфизма генов интерлейкинов и цитокиновый баланс женщин с невынашиванием беременности. Акушерство и гинекология. 2014, 3, 33–38.
- Симбирцев А. С. Цитокины в патогенезе инфекционных и неинфекционных заболеваний человека. Медицинский академический журнал. 2013, 13(3), 18–41.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).