EFFECTS OF GENETIC FACTORS TO INHALED CORTICOSTEROID RESPONSE IN CHILDREN WITH ASTHMA: A LITERATURE REVIEW
- Authors: Serezhkina A.V.1, Bogomazov A.D.1, Polonikov A.V.1
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Affiliations:
- Kursk State Medical University
- Issue: Vol 22, No 2-1 (2019)
- Pages: 530-531
- Section: ORIGINAL ARTICLES
- Submitted: 18.05.2020
- Accepted: 18.05.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/207
- DOI: https://doi.org/10.31857/S102872210006954-4
- ID: 207
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Abstract
Numerous studies have studied the Association between pharmacogenetic eff ects and response to inhaled glucocorticosteroids (ICS) in patients with asthma. In fact, several single nucleotide polymorphisms of a number of candidate genes have been identifi ed that may aff ect the clinical response to ICS in children with atopic asthma (BA). The results obtained to date indicate various potential genetic factors associated with the reaction to IGCs, which can be used to predict the individual therapeutic response of children with atopic asthma to ICS.
Keywords
About the authors
A. V. Serezhkina
Kursk State Medical University
Author for correspondence.
Email: aleksandra.ykv@gmail.com
assistant of the Department of Pediatrics,
Kursk
Russian FederationA. D. Bogomazov
Kursk State Medical University
Email: fake@neicon.ru
PhD, associate Professor of the Department of Pediatrics,
Kursk
Russian FederationA. V. Polonikov
Kursk State Medical University
Email: fake@neicon.ru
MD, Professor Department of biology, medical genetics and ecology,
Kursk
Russian FederationReferences
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