THE EFFECT OF CHICKEN YOLK IMMUNOGLOBULIN Y ON INCREASE IN EDURANCE OF MICE

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Abstract

The evaluation of adaptogenic properties of lyophilized immunoglobulins Y isolated from chicken yolks was performed with biological testing methods (IgY). In animal experiments, in the forced swimming test (FST), a prior five- and ten-fold oral administration of yolk chicken IgY in a dose of 2 mg per mouse led to a relevant increase in animal endurance.

About the authors

V. S. Kaplin

FBRI State Research Center of Virology and Biotechnology «Vector»

Author for correspondence.
Email: kaplin_vs@vector.nsc.ru

Pb D., SRF,

Koltsovo, Novosibirsk Region

Russian Federation

G. M. Sysoeva

Institute of Medical Biotechnology FBRI State Research Center of Virology and Biotechnology «Vector»

Email: fake@neicon.ru

SRF, 

Berdsk, Novosibirsk Region

Russian Federation

L. V. Gridunova

ZAO Altaivitaminy

Email: fake@neicon.ru

chief technologist,

Altai region, Biysk

Russian Federation

N. I. Kuleshova

ZAO Altaivitaminy

Email: fake@neicon.ru

Ph D., chief development officer,

Altai region, Biysk

Russian Federation

L. R. Lebedev

Institute of Medical Biotechnology FBRI State Research Center of Virology and Biotechnology «Vector»

Email: fake@neicon.ru

Dr. habil., Head of the laboratory of Nucleic Acids and Recombinant Proteins,

Berdsk, Novosibirsk Region

Russian Federation

References

  1. Hodek, P. Trefi l, J. Simunek, J. Hudecek, M. Stiborova. Optimized Protocol of Chicken Antibody (IgY) Purification Providing Electrophoretically Homogenous Preparations. Int. J. Electrochem. Sci. 2013, 8, 113–124.
  2. Karkischenko V. N., FokinYu.V., KazakovaL.Kh., Alimkina O. V., Kasinskaya N. V. Methods of studying physiological functions of laboratory animals for preclinical researches in sports medicine. Biomeditsina (Rus.) 2012, 4, 15–21.

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Copyright (c) 2019 Kaplin V.S., Sysoeva G.M., Gridunova L.V., Kuleshova N.I., Lebedev L.R.

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