Email this article LABORATORY POSSIBILITY IN THE DIAGNOSIS OF DRUG HYPERSENSITIVITY
- Authors: Bychkova N.V.1,2
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Affiliations:
- NRCERM EMERCOM of Russia
- Saint-Petersburg State Medical University named after I. P. Pavlov
- Issue: Vol 22, No 2-1 (2019)
- Pages: 180-182
- Section: ORIGINAL ARTICLES
- Submitted: 12.04.2020
- Accepted: 12.04.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/37
- DOI: https://doi.org/10.31857/S102872210006446-5
- ID: 37
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Abstract
Drug hypersensitivity reactions are not very common in the population, but can be a serious problem for patients and physicians. Diagnosis of this disorder should consist of a complex of clinical and laboratory methods. A promising method of in vitro diagnostics is the basophil activation test. The study showed the high diagnostic significance of this test in determining hypersensitivity to radiocontrast media and local anesthetics. The presence of in vitro hypersensitivity to drugs can be latent in nature and manifest itself clinically only if the regulatory capabilities are impaired.
About the authors
N. V. Bychkova
NRCERM EMERCOM of Russia;Saint-Petersburg State Medical University named after I. P. Pavlov
Author for correspondence.
Email: BNV19692007@yandex.ru
PhD, Senior Researcher of the Laboratory of Clinical Immunology of the Department of Laboratory Diagnostics;
Assistant-Professor of the Department of Immunology,
Saint-Petersburg
Russian FederationReferences
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