Email this article ANTIPATERNAL ANTI-LEUKOCYTE ANTIBODIES AS MARKERS OF THE EFFICACY OF ALLOIMMUNIZATIONIN WOMEN WITH RECURRENT PREGNANCY LOSS
- Authors: Vtorushina V.V.1, Krechetova L.V.1, Tetruashvili N.K.1, Nikolaeva M.A.1
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Affiliations:
- Federal State Budget Institution «National medical research center of obstetrics, gynecology and Perinatology» of the Ministry of health of Russia
- Issue: Vol 22, No 2-1 (2019)
- Pages: 194-196
- Section: ORIGINAL ARTICLES
- Submitted: 13.04.2020
- Accepted: 13.04.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/42
- DOI: https://doi.org/10.31857/S102872210006454-4
- ID: 42
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Abstract
The indicator of efficacy of lymphocyte immunotherapy (LIT) in women with recurrent pregnancy loss(RPL) is the level of antipaternal anti-leukocyte antibodies (APAB) detected by method of flow cytometry. The article presents the results of determining APAB in the dynamics of pregravid preparation and pregnancy in women with RPL and pregnancy outcomes after LIT.
About the authors
V. V. Vtorushina
Federal State Budget Institution «National medical research center of obstetrics, gynecology and Perinatology» of the Ministry of health of Russia
Author for correspondence.
Email: vtorushina@inbox.ru
Ph.D. in medical sciences, allergist-immunologist, doctor of laboratory diagnostics in Laboratory of Clinical Immunology,
Moscow
Russian FederationL. V. Krechetova
Federal State Budget Institution «National medical research center of obstetrics, gynecology and Perinatology» of the Ministry of health of Russia
Email: fake@neicon.ru
Ph.D. in medical sciences, Head of Laboratory of Clinical Immunology,
Moscow
Russian FederationN. K. Tetruashvili
Federal State Budget Institution «National medical research center of obstetrics, gynecology and Perinatology» of the Ministry of health of Russia
Email: fake@neicon.ru
Doctor of Medicine, Head of the Department of Pregnancy Loss Prevention and Therapy,
Moscow
Russian FederationM. A. Nikolaeva
Federal State Budget Institution «National medical research center of obstetrics, gynecology and Perinatology» of the Ministry of health of Russia
Email: fake@neicon.ru
Doctor of Science, Leading researcher, Laboratory of Clinical Immunology,
Moscow
Russian FederationReferences
- Кречетова Л. В., Тетруашвили Н. К., Вторушина В. В., Николаева М. А., Голубева Е. Л., Сарибегова В. А., Агаджанова А. А., Ванько Л. В. Динамика выработки антилейкоцитарных антител в течение беременности у женщин с привычным выкидышем на фоне иммуноцитотерапии. Акушерство и гинекология. 2017, 9, 49–55.
- Кречетова Л. В., Николаева М. А., Ванько Л. В., Зиганшина М. М., Голубева Е. Л., Степанова Е. О., Сухих Г. Т. Оптимизация выявления антиотцовских антилейкоцитарных антител в сыворотке крови женщин с привычным невынашиванием после введения аллогенных лимфоцитов. Бюллетень экспериментальной биологии и медицины. 2012, Т. 153, 5, 684–688.
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