Email this article SUBPOPULATIONS OF MYELOID DERIVED SUPRESSORS CELLS IN CHILDREN WITH PSORIASIS
- Authors: Gerasimova D.G.1, Radygina T.V.1, Zakirov R.S.1, Ambarchyan A.I.1, Materikin A.I.1, Epishev N.N.1, Murashkin A.I.1, Petrichuk S.V.1
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Affiliations:
- National Medical Research Center for Children’s Health
- Issue: Vol 22, No 2-1 (2019)
- Pages: 200-201
- Section: ORIGINAL ARTICLES
- Submitted: 13.04.2020
- Accepted: 13.04.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/44
- DOI: https://doi.org/10.31857/S102872210006457-7
- ID: 44
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Abstract
The absolute and relative number of myeloid derived suppressor cells, regulatory T-lymphocytes and Th17-lymphocytes were assessed in 115 patients with psoriasis and 53 healthy children aged 1.5 to 18 years. An increase in the number of MDSCs due to G-MDSCs was found, depending on the duration of the disease. As the severity of the disease increases, the relative number of M-MDSCs increases. The number of MDSCs directly correlates with the number of Th17 lymphocytes and Treg.
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About the authors
D. G. Gerasimova
National Medical Research Center for Children’s Health
Email: fake@neicon.ru
resident, Laboratory of Experimental Immunology and Virology,
Moscow
Russian FederationT. V. Radygina
National Medical Research Center for Children’s Health
Email: fake@neicon.ru
Ph D., Senior Research Associate, Laboratory of Experimental Immunology and Virology,
Moscow
Russian FederationR. Sh. Zakirov
National Medical Research Center for Children’s Health
Email: fake@neicon.ru
Doctor of clinical laboratory,
Moscow
Russian FederationA. I. Ambarchyan
National Medical Research Center for Children’s Health
Email: fake@neicon.ru
Research Associate, Laboratory Skin Phatology in children,
Moscow
Russian FederationA. I. Materikin
National Medical Research Center for Children’s Health
Email: fake@neicon.ru
Dermatologist, Department of Dermatology,
Moscow
Russian FederationN. N. Epishev
National Medical Research Center for Children’s Health
Email: fake@neicon.ru
Dermatovenerologist, Department of Dermatology,
Moscow
Russian FederationA. I. Murashkin
National Medical Research Center for Children’s Health
Email: fake@neicon.ru
PhD, MD, Head of the Laboratory Skin Phatology in children,
Moscow
Russian FederationS. V. Petrichuk
National Medical Research Center for Children’s Health
Author for correspondence.
Email: cito@list.ru
PhD, MD (Biology), Professor, Principal Research Associate, Laboratory of Experimental Immunology and Virology,
Moscow
Russian FederationReferences
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- Zhu J., Chen S., Wu L., Wang R., Zheng S., Zhao D., Wang X, Li J. The Expansion of Myeloid-Derived Suppressor Cells Is Associated with Joint Infl ammation in Rheumatic Patients with Arthritis // Bio Med Research International, Vol. 2018, Article ID5474828, 12 p.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).