RECEPTOR AND PHAGOCYTIC ACTIVITY OF NEUTROPHILS IN CHRONIC DISEASES OF THE UPPER GASTROINTESTINAL TRACT IN CHILDREN, ASSOCIATED WITH HELICOBACTER PYLORI, AND FUNGI OF THE GENUS CANDIDA

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Abstract

In children with chronic diseases of the upper gastrointestinal tract associated with Helicobacter pylori, and Helicobacter pylori association with fungi of the genus Candida, study of the receptor apparatus (adhesion, to the components of complement-CR 3, Fc fragment of Ig G and activation markers) and phagocytic activity of neutrophils. The identified differentiated characteristics of the phagocytic activity and immunophenotype in Helicobacter pylori infection and association with fungi of the genus Candida. Mannoproteins circulating antigen of Candida albicans affects the immunophenotype of neutrophils, inducing the expression of proapoptotic and reducing the expression of adhesion receptors and cytolysis.

About the authors

E. V. Agafonova

Kazan state medical University FBUN KNIIM Central research Institute of Rospotrebnadzor

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

T. A. Velinsky

Kazan state medical University FBUN KNIIM Central research Institute of Rospotrebnadzor

Email: noemail@neicon.ru
Russian Federation

References

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  3. Нестерова И.В., Швыдчеко И. Н., Роменская В. А. и др. Нейтрофильные гранулоциты - ключевые клетки иммунной системы. Аллергология и иммунология 2008, 4, 432-435.
  4. Wormley F. L., Chaiban].R., Fidel P. L. Cell adhesion molecule and lymphocyte activation marker expression during experimental vaginal candidiasis. Infect. Immun.2001,8(suppl.),5072-5079.
  5. Han Y., Ulrich M. A., Cutler].E. Candida albicans mannan extract-protein conjugates induce immune response against experimental candidiasis. J. Infect. Dis. 2009, 6(suppl.), 1477-1484.

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Copyright (c) 2017 Agafonova E.V., Velinsky T.A.

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