Email this article REACTION OF IMMUNOCOMPETENT CELLS TO KIDNEY ALTERATION IN EXPERIMENTAL ALLOXAN DIABETES
- Authors: Blinkova N.B.1, Danilova I.G.1, Gette I.F.1, Bulavintseva T.S.1
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Affiliations:
- Ural Federal University, Institute of Immunology and physiology UB RAS
- Issue: Vol 20, No 2 (2017)
- Pages: 257-258
- Section: Articles
- URL: https://rusimmun.ru/jour/article/view/645
- ID: 645
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Abstract
The reaction of immunocompetent cells to renal alteration was studied on the model of alloxan diabetes in rats. The growing structural violations in the kidney in a chronic hyperglycemia accompanied by increased migration of leukocytes, T-lymphocytes and a decrease in the number of B-lymphocytes and macrophages in the stroma of the organ.
About the authors
N. B. Blinkova
Ural Federal University, Institute of Immunology and physiology UB RAS
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
I. G. Danilova
Ural Federal University, Institute of Immunology and physiology UB RAS
Email: noemail@neicon.ru
Russian Federation
I. F. Gette
Ural Federal University, Institute of Immunology and physiology UB RAS
Email: noemail@neicon.ru
Russian Federation
T. S. Bulavintseva
Ural Federal University, Institute of Immunology and physiology UB RAS
Email: noemail@neicon.ru
Russian Federation
References
- Дзугкоев С. Г., Дзугкоева Ф. С. Патогенетические аспекты диабетической нефропатии при экспериментальном сахарном диабете у крыс. Современные наукоемкие технологии, 2007, 3, 44-46.
- Шестакова М. В., Дедов И. И. Сахарный диабет и хроническая болезнь почек. Москва: ООО «Медицинское информационное агентство», 2009, 482.
- Chow F. Y., Nikolic-Paterson D.J., Atkins R. C., Tesch G. H. Macrophages in streptozotocin-in-duced diabetic nephropathy: potential role in renal fibrosis. Nephrol. Dial. Transplant, 2004, 19, 2987-2996.
- Danilova I. G., Sarapultsev P. A., Medvedeva S. U. Morphological restructuring of myocardium during the early phase of experimental diabetes mellitus. Anat. Rec. (Hoboken), 2015, 298(2), 396-407.
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