ROLE OF HOMOSERINLACLONTS IN SALMONELLA SURVIVAL DURING PHAGOCYTOSIS

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Abstract

Described increase in the virulence of Salmonella in the presence of small regulatory molecules. The influence of homoserine, among which the most important role played by N-(3-oxo-hexanoyl)-homos-erine lactone, on the induction of the promoter rck the strain S. typhimurium LT2, which determines the resistance of the complement system. Revealed increased resistance of the strain to phagocytosis in the presence of homoserine.

About the authors

O. V. Grigoreva

Orenburg State University

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

I. F. Karimov

Orenburg State University

Email: noemail@neicon.ru
Russian Federation

References

  1. Гинцбург А.Л. «Quorum sensing» или социальное поведение бактерий / А. Л. Гинцбург, Ю. М. Романова, Т. С. Ильина // Микробиология.- 2003.Т. 5.- С. 86-93.
  2. Michael, B. SdiA of Salmonella enterica is a LuxR homolog that detects mixed microbial communities / B. Michael, J. N. Smith, S. Swift, F. Heffron, B. M. Ahmer // Journal of bacteriology.- 2011.- V. 183.- P. 5733-5742.
  3. Holm A. Pseudomonas aeruginosa N-3-oxo-dodeca-noyl-homoserine Lactone Elicits Changes in Cell Volume, Morphology, and AQP9 Characteristics in Macrophages // А. Holm, K. E. Magnusson, Е. Vikstrom // Front Cell Infect Microbiol.- 2016.- V. 6.- P. 32.

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Copyright (c) 2017 Grigoreva O.V., Karimov I.F.

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