THE DISTRIBUTION OF GENES AND HAPLOTYPES HLA II CLASS IN NAGAIBAKS POPULATION IN COMPARISON WITH OTHER POPULATIONS OF THE CHELYABINSK REGION AND EURASIA

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Abstract

The issues of populational immunogenetics are described in this article. In particular, the comparative characteristic of the frequencies of HLA II class genes and haplotypes in Nagaibaks population with the main populations of the Chelyabinsk region (Russian, Tatars and Bashkirs) is analyzed. Genetic distances on HLA II class genes between Nagaibaks population and some populations of Eurasia are constructed. The results of our research show, that population Nagaibaks is largely different from the population of Bashkirs of Chelyabinsk region on the frequencies of genes and haplotypes of HLA II class. According to the assessment of genetic distances on the HLA II class genes populations of Russian, Tatar population of the Chelyabinsk region and the Chuvash are the nearest to Nagaibaks population.

About the authors

O. N. Zaripova

Chelyabinsk State University

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

S. V. Belyaeva

Chelyabinsk State University; Chelyabinsk Regional blood transfusion station

Email: noemail@neicon.ru
Russian Federation

D. S. Stashkevich

Chelyabinsk State University

Email: noemail@neicon.ru
Russian Federation

T. A. Suslova

Chelyabinsk State University; Chelyabinsk Regional blood transfusion station

Email: noemail@neicon.ru
Russian Federation

References

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  2. Downing, J., Guttridge, M.G., Thompson, J. & Darke, C. (2004) Five-locus HLA typing of hematopoietic stem cell donor volunteers using PCR sequence specific primers. Genetic Testing, 8, 301
  3. Excoffier, L. Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows / L. Excoffier, HE. Lis-cher // Molecular Ecology Resources.- 2010.- Vol. 10, Is. 3.- P. 564-567.
  4. The Allele Frequency Net Database [Электронный ресурс]. - URL: http://www.allelefrequencies.net. (дата обращения: 13.12.2016).

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Copyright (c) 2017 Zaripova O.N., Belyaeva S.V., Stashkevich D.S., Suslova T.A.

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