Email this article INFLUENCE OF INTESTINE MICROSYMBIONTS METABOLITES ON THE PRODUCTION OF NITRIC OXIDE BY PERITONEAL MACROPHAGES
- Authors: Ivanova E.V.1, Bondarenko T.A.1, Chainikova I.N.1, Bukharin O.V.1
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Affiliations:
- "Institute of Cellular and Intracellular Symbiosis"
- Issue: Vol 20, No 2 (2017)
- Pages: 338-340
- Section: Articles
- Submitted: 22.10.2020
- Published: 15.04.2017
- URL: https://rusimmun.ru/jour/article/view/678
- ID: 678
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Abstract
Metabolites of clinical cultures Clostridium spp., Staphylococcus spp., Bacteroides spp. significantly inhibited in vitro basal secretion by peritoneal macrophages (MF) of nitric oxide (NO) mice. In contrast, metabolites of Bifidobacterium spp., Lactobacillus spp. and Propionibacterium spp. moderately stimulated the NO secretion. The overall effect of the metabolites influence of intestinal microsymbionts on the functional activity of MF will be determined by their qualitative and quantitative composition in the human intestine eubiosis and dysbiosis.
About the authors
E. V. Ivanova
"Institute of Cellular and Intracellular Symbiosis"
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
T. A. Bondarenko
"Institute of Cellular and Intracellular Symbiosis"
Email: noemail@neicon.ru
Russian Federation
I. N. Chainikova
"Institute of Cellular and Intracellular Symbiosis"
Email: noemail@neicon.ru
Russian Federation
O. V. Bukharin
"Institute of Cellular and Intracellular Symbiosis"
Email: noemail@neicon.ru
Russian Federation
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- Phenotypic Diversity and Emerging New Tools to Study Macrophage Activation in Bacterial Infectious iseases. Frontiers in Immunology / M. B. Ka, A. Daumas, J. Textoris et al. // 2014;5:500. doi: 10.3389/fimmu.2014.00500.
- Метаболический профиль бифидофлоры при различных микроэкологических состояниях биотопа толстого кишечника человека / О. В. Бухарин, Е. В. Иванова, Н. Б. Перунова и соавт. // Журн. микробиол. 2017.- № 1.- С. 3-11
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).