Use of Lectins for Analysis of Glycans in Recombinant Protein Biopharmaceuticals

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About the authors

V. . Monakhova

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

M. . Sushkin

Email: noemail@neicon.ru
Russian Federation

N. . Pigareva

Email: noemail@neicon.ru
Russian Federation

A. . Simbirtsev

Email: noemail@neicon.ru
Russian Federation

References

  1. Landemarre L., Duverger E. Lectin glycoprofi ling of recombinant therapeutic interleukin-7. In the book: Glycosylation engineering of biopharmaceuticals: Methods and protocols. Humana Press, 2013; 221–26.
  2. Hyoung J. K., Seung J. L., Kim H.-J. Antibody-based enzyme-linked lectin assay (ABELLA) for the sialylated recombinant human erythropoietin present in cell culture supernatant. Journal of Pharmaceutical and biomedical analysis. 2008, 48, 716–721.
  3. Павловская Н.Е, Гагарина И. Н. Функциональная роль лектинов растений как предпосылка для их применения в биотехнологии. Химия растительного сырья. 2017, 1, 21–35. [Pavlovskaya N. E., Gagarina I. N. Functional role of plant lectins as a premise for its application in biotechnology. Chemistry of vegetable raw materials. 2017, 1, 21–35]
  4. Wu J., Zhu J., Yin H., Buckanovich R. J., Lubman D. M. Analysis of glycan variation on glycoproteins from serum by the reverse lectin-based ELISA assay. Journal of proteome research. 2014, 13, 2197–2204.
  5. Thompson R., Creavin A., O’Connell M., O’Connor B., Clarke P. Optimization of the enzyme-linked lectin assay for enhanced glycoprotein and glycoconjugate analysis. Analytical Biochemistry. 2011, 413, 114–122.
  6. Gornik O., Lauc G. Enzyme linked lectin assay (ELLA) for direct analysis of transferrin sialylation in serum samples. Clinical Biochemistry. 2007, 40, 718–723.
  7. Zhang L., Luo S., Zhang B. The use of lectin microarray for assesising glycosylation of therapeutic proteins. Mabs. 2016, 8 (3), 524–535.
  8. Weber A., Minibeck E., Scheifl inger F., Turecek P. L. Development of a lectin binding assay to differentiate between recombinant and endogenous proteins in pharmacokinetics studies of protein-biopharmaceuticals. Journal of pharmaceuticals and biomedical analysis. 2015, 108, 21–28.

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