Immunological markers of early diagnostics of posttraumatic osteomielitis of the lower jaw
- Authors: Popova E..1, Kostushko A..1, Dubov V..1, Milekhina S..1
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Affiliations:
- Pacific State Medical University
- Issue: Vol 21, No 3 (2018)
- Pages: 402-406
- Section: ORIGINAL ARTICLES
- Submitted: 22.10.2020
- Published: 15.07.2018
- URL: https://rusimmun.ru/jour/article/view/902
- DOI: https://doi.org/10.31857/S102872210002418-4
- ID: 902
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Abstract
The article presents an assessment of the systemic level of tumor necrosis factor α, interferon γ, interleukin- 4, interleukin-10, matrix metalloproteinase-9 and tissue inhibitor-1 type in patients with posttraumatic osteomyelitis and uncomplicated mandible fractures. The study identifi ed indicators of the system of Pro-and anti-infl ammatory cytokines, indicating their signifi cant role in the immunopathogenesis of post-traumatic osteomyelitis of the mandible. Identifi cation of additional markers for the diagnosis of posttraumatic osteomyelitis of the mandible (TNF, IFN-γ, IL-10), the defi nition of which at the beginning of therapy and the dynamics of its implementation will allow for a more personalized approach to the management of this category of patients
About the authors
E. . Popova
Pacific State Medical University
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
A. . Kostushko
Pacific State Medical University
Email: noemail@neicon.ru
Russian Federation
V. . Dubov
Pacific State Medical University
Email: noemail@neicon.ru
Russian Federation
S. . Milekhina
Pacific State Medical University
Email: noemail@neicon.ru
Russian Federation
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