Email this article THE ROLE OF MACROPHAGES IN LOCAL REGULATION OF THE SYNTHETIC ACTIVITY OF INSULIN-SECRECTING PANCREATIC CELLS IN ALLOXANE DIABETES
- Authors: Bulavintseva T.S.1,2, Danilova I.G.1,2, Shmacova S.E.1,2
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Affiliations:
- 1Ural Federal University
- Institute of Immunology and physiology UB RAS
- Issue: Vol 20, No 2 (2017)
- Pages: 267-269
- Section: Articles
- Submitted: 22.10.2020
- Published: 15.04.2017
- URL: https://rusimmun.ru/jour/article/view/649
- ID: 649
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Abstract
On the alloxan diabetes model in rats, it was shown that exposure to monocytes / macrophages with an aminophthalhydroside derived drug leads to a decrease in monocyte infiltration and IL-1a in the pancreas. That promotes the preservation of insulin-producing cells and increases their synthetic activity.
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About the authors
T. S. Bulavintseva
1Ural Federal University; Institute of Immunology and physiology UB RAS
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
I. G. Danilova
1Ural Federal University; Institute of Immunology and physiology UB RAS
Email: noemail@neicon.ru
Russian Federation
S. E. Shmacova
1Ural Federal University; Institute of Immunology and physiology UB RAS
Email: noemail@neicon.ru
Russian Federation
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Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).