STEP-BY-STEP SIMULATION RISK REDUCTION OF PRIVATE ACUTE RESPIRATORY VIRAL INFECTION CASES IN PATIENTS WITH DIFFERENT IMMUNE STATUS
- Authors: Martynov A.I.1, Fedoskova T.G.1, Feofanova T.V.1, Zelenova Z.V.1
-
Affiliations:
- Federal Medical-Biological Agency of Russia National Research Center Institute of Immunology
- Issue: Vol 22, No 2-1 (2019)
- Pages: 400-402
- Section: ORIGINAL ARTICLES
- Submitted: 04.05.2020
- Accepted: 04.05.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/162
- DOI: https://doi.org/10.31857/S102872210006910-6
- ID: 162
Cite item
Full Text
Abstract
A step-by-step statistical model for calculating the risks of frequent annual cases of acute respiratory viral infection in adults in the conditions of changing the magnitude of the harmful eff ects is proposed. The algorithm was tested on the data of two groups of workers of the chemical enterprise, which diff ered in size of the corresponding immune markers. It is shown that with the same reduction in the level of harmful eff ects, the rate of risk reduction in the groups diff ered by 2.5 times. Thus, the model can be used to select a priority group of employees in the conditions of a given impact on the production factor in order to minimize the value of the specifi ed risk for them.
About the authors
A. I. Martynov
Federal Medical-Biological Agency of Russia National Research Center Institute of Immunology
Author for correspondence.
Email: fake@neicon.ru
Ph. D., first Deputy Director,
Moscow
Russian FederationT. G. Fedoskova
Federal Medical-Biological Agency of Russia National Research Center Institute of Immunology
Email: fake@neicon.ru
MD, Head of the laboratory of Molecular Mechanisms of Allergy,
Moscow
Russian FederationT. V. Feofanova
Federal Medical-Biological Agency of Russia National Research Center Institute of Immunology
Email: tatianafeofanova@yandex.ru
Phys.-MD., Leading Researcher., Laboratory of Immunological Processes modeling,
Moscow
Russian FederationZ. V. Zelenova
Federal Medical-Biological Agency of Russia National Research Center Institute of Immunology
Email: fake@neicon.ru
Researcher, Laboratory of Immunological Processes Modeling,
Moscow
Russian FederationReferences
- Мартынов А. И., Федоскова Т. Г., Феофанова Т. В., Зеленова З. В. Иммунные маркеры повышенного риска частых случаев острой респираторной вирусной инфекции у работников химического производства Российский иммунологический журнал. 2017, 11, 3, 419–421.
- Richter J., Pelech L. Immunological fi ndings in groups of children after compensatory measures. Toxicol Lett. 1996, 88, 1–3, 165–168.
- Мартынов А. И., Федоскова Т. Г., Феофанова Т. В., Зеленова З. В. Некоторые аспекты управления рисками ежегодных случаев острой респираторной вирусной инфекции в группах лиц с разным иммунным статусом. В кн.: Управление развитием крупномасштабных систем (MLSD’2018) Труды одиннадцатой международной конференции. ИПУ РАН, Москва 2018, 391–399.