Email this article ASSESSMENT OF CORRELATION BETWEEN CYTOKINE STATUS AND RED CELL DISTRIBUTION WIDTH IN PATIENTS WITH ATHEROSCLEROSIS OF LOWER LIMBS AFFECTED BY DIABETES MELLITUS TYPE 2
- Authors: Savchuk K.S.1, Ryabova L.V.2, Nikushkina K.V.2, Nikonova T.I.2
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Affiliations:
- Municipal budgetary healthcare institution city clinic outpatient clinic No 8
- Federal state budgetary educational institution of higher education “South Ural State Medical University”
- Issue: Vol 22, No 2-1 (2019)
- Pages: 509-511
- Section: ORIGINAL ARTICLES
- Submitted: 14.05.2020
- Accepted: 14.05.2020
- Published: 15.04.2019
- URL: https://rusimmun.ru/jour/article/view/200
- DOI: https://doi.org/10.31857/S102872210006947-6
- ID: 200
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Abstract
Research’s objective is to make an analysis of correlations between index of systemic inflammation and red cell distribution width in patients with diabetes mellitus type 2 aff ected by atherosclerosis of lower limbs. 40 patients with diabetes mellitus were examined. Using Spearmen rank correlation, statistically signifi cant correlations between IL-1β and red cell distribution width were discovered (r=0,358; p=0,027). Herewith there is no signifi cant correlation between IL-6, IL-8, IL-10, TNF-α and red cell distribution width.
About the authors
K. S. Savchuk
Municipal budgetary healthcare institution city clinic outpatient clinic No 8
Author for correspondence.
Email: ksenyasavchuk@gmail.com
chief operating officer,
Chelyabinsk
Russian FederationL. V. Ryabova
Federal state budgetary educational institution of higher education “South Ural State Medical University”
Email: fake@neicon.ru
holder of Habilitation degree in medicine, professor of Propaedeutics of Internal Diseases,
Chelyabinsk
Russian FederationK. V. Nikushkina
Federal state budgetary educational institution of higher education “South Ural State Medical University”
Email: fake@neicon.ru
senior researcher of Research institute of immunology,
Chelyabinsk
Russian FederationT. I. Nikonova
Federal state budgetary educational institution of higher education “South Ural State Medical University”
Email: fake@neicon.ru
senior assistant of Research institute of immunology,
Chelyabinsk
Russian FederationReferences
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- Malandrino N., Wu W., Taveira T. Association between red blood cell distribution width and macrovascular and microvascular complications in diabetes. Diabetologia, 2012, 55 (1), 226–235.
- de Gonzalo-Calvo D., de Luxan-Delgado B., RodrgiuezGonzalez S. Interleukin 6, soluble tumor necrosis factor receptor I and red blood cell distribution width as biological markers of functional dependence in an elderly population: a translational approach. Cytokine, 2012, 58 (2), 193–198.
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