STANDARD TREATMENT IN THE CORRECTION OF IMMUNE DISTURBANCES IN ACUTE SEROUS AND PURULENT PYELONEPHRITIS

Objective: to study the eff ectiveness of the basic treatment of acute pyelonephritis in terms of immune status.

Materials and methods. The immune status of 62 patients with various forms of acute pyelonephritis.

Results. and its discussion. When serous and purulent forms of acute pyelonephritis are observed: increased levels of cytokines with a decrease in anti-infl ammatory with purulent pyelonephritis and their imbalance ‒ with serous form, an imbalance in the complement system, increased production of immunoglobulins with a simultaneous decrease in CIC, reduced activity and intensity of phagocytosis in the background of increased metabolic activity.

Conclusion. With serous and purulent forms of pyelonephritis, there are diff erences in the direction and severity of changes in immune parameters that do not normalize after treatment, which requires the development of additional methods of immunocorrection and immunorehabilitation.