ABILITY OF CONDITIONALLY-PATHOGENIC MICROORGANISM TO INACTIVATE ANTI-MICROBIAL PROTEIN BY LYSOZYM UNDER THE INFLUENCE OF METABOLITES ASSOCIATION OF BIFIDOBACTERIA

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Abstract

Materials on the eff ect of the supernatants of the associations of bifi dobacteria on the antilysozyme activity of microorganisms are presented. An increase in the antilysozyme activity was detected in the lactosopositive non-hemolytic strains of E. coli isolated during human intestinal eubiosis, and, conversely, a decrease in hemolytic E. coli, S. aureus and C. albicans isolated in dysbiosis. The available materials contribute to the study of the mechanisms of formation of microsymbiosis in the associative symbiosis of humans and contribute to the identifi cation of strains of bifi dobacteria, suitable as pro- and metabiotics.

About the authors

A. V. Bekpergenova

FGBUN Institute for Cellular and Intracellular Symbiosis

Author for correspondence.
Email: nsavasteeva@gmail.com

Researcher, Laboratory of Biomonitoring and Molecular Genetic Research,

Orenburg

Russian Federation

N. B. Perunova

FGBUN Institute for Cellular and Intracellular Symbiosis

Email: fake@neicon.ru

PhD, Professor RAS, Associate Professor Laboratory of Biomonitoring and Molecular Genetic Research, 

Orenburg

Russian Federation

S. V. Andryushenko

FGBUN Institute for Cellular and Intracellular Symbiosis

Email: fake@neicon.ru

PhD, Associate Professor Laboratory of Biomonitoring and Molecular Genetic Research,

Orenburg

Russian Federation

I. A. Zdvizhkova

FGBUN Institute for Cellular and Intracellular Symbiosis

Email: fake@neicon.ru

Researcher, Laboratory of Biomonitoring and Molecular Genetic Research,

Orenburg

Russian Federation

A. R. Mironova

GBUZ Orenburg Regional Clinical Infectious Diseases Hospital, Orenburg

Email: fake@neicon.ru

Head of Bacteriological Laboratory, 

Orenburg

Russian Federation

References

  1. Бухарин О. В. Персистенция патогенных бактерий. М.: Медицина, 1999, 322.
  2. Шендеров Б. А. Медицинская микробная экология и функциональное питание. М.: ГАРАНТЪ. 1998, 1, 288.

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Copyright (c) 2019 Bekpergenova A.V., Perunova N.B., Andryushenko S.V., Zdvizhkova I.A., Mironova A.R.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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