POSTSTRESSOR CHANGES IN FUNCTIONAL ACTIVITY OF CELLS OF PERITONEAL CAVITY OF MICE
- Authors: Sharav’eva I.L.1, Gein S.V.1,2
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Affiliations:
- Institute of Ecology and Genetics of Microorganisms, UrB RAS
- Perm State University
- Issue: Vol 22, No 3 (2019)
- Pages: 1308-1312
- Section: ORIGINAL ARTICLES
- Submitted: 13.09.2020
- Accepted: 13.09.2020
- Published: 15.10.2019
- URL: https://rusimmun.ru/jour/article/view/524
- DOI: https://doi.org/10.31857/S102872210007278-0
- ID: 524
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Full Text
Abstract
The effect of acute and chronic cold stress in the conditions of the blockade of opiate receptors on the oxidative activity of mouse peritoneal macrophages was studied. It was established that acute cold stress (4°C, 4 hours), regardless of the blockade of opiate receptors, inhibits zymosan-induced oxidative activity of mouse peritoneal macrophages. Chronic cold stress (4°C, 4 hours, for 7 days) on the 7th day activates zymosan-induced oxidative activity of macrophages, blockade of opiate receptors leads to the cancellation of this stimulation. An increase in the concentration of corticosterone is observed both in acute and in chronic hypothermia and does not depend on the blockade of opiate receptors.
About the authors
I. L. Sharav’eva
Institute of Ecology and Genetics of Microorganisms, UrB RAS
Author for correspondence.
Email: irin.sh@gmail.com
PhD Biological Sciences, scientifi c researcher of the laboratory of biochemistry of microorganism development of the Institute of Ecology and Genetics of Microorganisms,
Perm
Russian FederationS. V. Gein
Institute of Ecology and Genetics of Microorganisms, UrB RAS;Perm State University
Email: fake@neicon.ru
MD, Professor, deputy director for research at the Institute of Ecology and Genetics of Microorganisms;
professor of the Department of microbiology and immunology of the Biology Faculty,
Perm
Russian FederationReferences
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